{"orpha":183713,"name":"OBSOLETE: Bacterial susceptibility due to TLR signaling pathway deficiency","type":"Disease","group":"Disorder","status":"inactive","flags":["Obsolete entity"],"synonyms":[],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>Instead, consider using Transient predisposition to invasive pyogenic bacterial infection","url":"https://raremap.alftech.space/d/ORPHA-183713/","orphanet_url":"https://www.orpha.net/en/disease/detail/183713","names":{"fr":{"name":"OBSOLETE : Susceptibilité bactérienne dépendante de la voie TLR"},"de":{"name":"OBSOLET: Suszeptibilität für Bakterieninfektion durch TLR Signalweg-Defizienz"},"es":{"name":"OBSOLETO: Susceptibilidad a infecciones bacterianas por deficiencia de la vía de señalización TLR"},"it":{"name":"OBSOLETO: Suscettibilità batterica da deficit della via di segnalazione di TLR","synonyms":["OBSOLETO: Deficit di MyD88"]},"nl":{"name":"OBSOLEET: Vatbaarheid voor bacteriële infectie door deficiëntie van TLR-signaalweg"},"pt":{"name":"OBSOLETO: Infeções bacterianas piogénicas por deficiência de MyD88"},"pl":{"name":"NIEAKTUALNE: Podatność na ropne zakażenia bakteryjne z powodu niedoboru szlaku sygnałowego TLR","synonyms":["NIEAKTUALNE: Niedobór MyD88"]},"cs":{"name":"NEAKTUÁLNÍ: Citlivost bakterií způsobená deficitem signální dráhy TLR","synonyms":["NEAKTUÁLNÍ: Deficit MyD88"]},"uk":{"name":"Бактеріальна чутливість, спричинена дефіцитом сигнального шляху TLR","definition":"Pyogenic bacterial infection due to MyD88 deficiency is a primary immunodeficiency characterized by increased susceptibility to pyogenic bacterial infections, including invasive pneumococcal, invasive staphylococcal and pseudomonas disease."},"zh":{"name":"TLR信号通路缺陷所致细菌易感性","definition":"TLR信号通路缺陷所致细菌易感性是一种原发性免疫缺陷，由于MYD88基因缺陷所致，其主要临床表现为易感染化脓性细菌，包括侵袭性肺炎球菌、侵袭性葡萄球菌和假单胞菌病。"},"tr":{"name":"TLR sinyal yolu eksikliğine bağlı bakteriyel duyarlılık"}},"xrefs":[],"associations":[{"type":"Referred to","orpha":70592,"name":"Transient predisposition to invasive pyogenic bacterial infection"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}