{"orpha":183669,"name":"Agammaglobulinemia","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-183669/","orphanet_url":"https://www.orpha.net/en/disease/detail/183669","names":{"fr":{"name":"Agammaglobulinémie"},"de":{"name":"Agammaglobulinämie"},"es":{"name":"Agammaglobulinemia"},"it":{"name":"Agammaglobulinemia"},"nl":{"name":"Agammaglobulinemie"},"pt":{"name":"Agamaglobulinemia"},"pl":{"name":"Agammaglobulinemia"},"cs":{"name":"Agamaglobulinémie"},"uk":{"name":"Агаммаглобулінемія"},"zh":{"name":"丙种球蛋白缺乏血症"},"tr":{"name":"Agamaglobulinemi"}},"xrefs":[{"source":"MONDO","code":"0015977","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"15977","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D000361","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0001768","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10001471","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":101977,"name":"Immunodeficiency due to predominantly antibodies defect","classifications":[156,195]}],"children":[{"orpha":229717,"name":"Non-syndromic agammaglobulinemia","type":"Disease"},{"orpha":229720,"name":"Syndromic agammaglobulinemia","type":"Category"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.13,"area":"Europe","status":"Not yet validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.287,"area":"France","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.134,"area":"Spain","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.192,"area":"Netherlands","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.045,"area":"Turkey","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.094,"area":"United Kingdom","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.205,"area":"Italy","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.077,"area":"Germany","status":"Validated","source":"22288591[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.071,"area":"Poland","status":"Validated","source":"22288591[PMID]"}],"phenotypes":null}