{"orpha":180182,"name":"Supernumerary breasts","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["Polymastia","Accessory breasts"],"definition":"A rare breast malformation characterized by the presence of accessory breasts with a complete ductal system, areola, and nipple in addition to two normal breasts. The accessory breast tissue mostly lies along the milk lines. It is often not recognized until puberty, when it begins to respond to regular hormonal fluctuations, and may develop the same changes as normal breasts throughout life.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-180182/","orphanet_url":"https://www.orpha.net/en/disease/detail/180182","names":{"fr":{"name":"Sein surnuméraire","synonyms":["Polymastie"],"definition":"Malformation mammaire rare caractérisée par la présence, en plus des deux seins normaux, de seins accessoires avec un système canalaire complet, une aréole et un mamelon. Le tissu mammaire accessoire se situe principalement le long des lignes de lait. Souvent identifié à la puberté, lorsqu'il commence à réagir aux changements hormonaux physiologiques, le sein surnuméraire peut subir tout au long de la vie les changements similaires à ceux affectant les seins normaux."},"de":{"name":"Brustdrüse, überzählige","synonyms":["Brustdrüse, akzessorische","Polymastie"],"definition":"Eine seltene Fehlbildung der Brust, die durch das Vorhandensein von akzessorischen Brüsten mit vollständigem Gangsystem, Warzenhof und Brustwarze zusätzlich zu zwei normalen Brüsten gekennzeichnet ist. Das akzessorische Brustgewebe liegt meist entlang der Milchleisten. Es wird oft erst in der Pubertät erkannt, wenn es auf die regelmäßigen Hormonschwankungen zu reagieren beginnt, und kann im Laufe des Lebens die gleichen Veränderungen wie die normalen Brüste entwickeln."},"es":{"name":"Mamas supernumerarias","synonyms":["Mamas accesorias","Polimastia"],"definition":"Es una malformación mamaria poco frecuente caracterizada por la presencia de mamas accesorias con un sistema ductal completo, areola y pezón, además de las dos mamas normales. El tejido mamario accesorio se distribuye principalmente a lo largo de las líneas mamarias. A menudo no se reconoce hasta la pubertad, cuando comienza a responder a las fluctuaciones hormonales regulares, pudiendo experimentar los mismos cambios que los senos normales durante toda la vida."},"it":{"name":"Mammelle soprannumerarie","synonyms":["Mammelle accessorie","Polimastia"],"definition":"Si tratta di una malformazione rara della mammella, caratterizzata dalla presenza di mammelle accessorie con un sistema duttale completo, areola e capezzolo, in aggiunta alle due normali mammelle. Il tessuto mammario accessorio si localizza per lo più lungo le linee del latte. La malformazione spesso non viene diagnosticata fino alla pubertà, quando inizia a rispondere alle regolari fluttuazioni ormonali, e può sviluppare gli stessi cambiamenti cui vanno incontro le mammelle normali nel corso della vita."},"nl":{"name":"Surnumeraire borsten","synonyms":["Accessoire borsten","Polymastie"],"definition":"Een zeldzame malformatie van borst, gekarakteriseerd door de aanwezigheid van accessoire borsten met volledig kanaalsysteem, tepelhof en tepel, bovenop twee normale borsten. Het accessoire borstweefsel ligt vooral langs de melklijsten. Het wordt vaak niet herkend tot in de puberteit, wanneer het begint te reageren op regelmatige hormonale schommelingen, en het kan doorheen de levensloop dezelfde veranderingen ondergaan als normale borsten."},"pt":{"name":"Mamilos supranumerários"},"pl":{"name":"Piersi dodatkowe","synonyms":["Dodatkowe piersi","Polymastia"]},"cs":{"name":"Nadpočetná prsní žláza","synonyms":["Akcesorní prsní žláza","Polymastie"]},"uk":{"name":"Додаткові груди","synonyms":["Додаткові груди","Полімастія"],"definition":"A rare breast malformation characterized by the presence of accessory breasts with a complete ductal system, areola, and nipple in addition to two normal breasts. The accessory breast tissue mostly lies along the milk lines. It is often not recognized until puberty, when it begins to respond to regular hormonal fluctuations, and may develop the same changes as normal breasts throughout life."},"zh":{"name":"多乳房","synonyms":["副乳房"],"definition":"多乳房症是一种罕见的乳房畸形，其主要临床表现为除两个正常乳房外，还有具有完整的导管系统、乳晕和乳头的副乳。副乳通常位于乳房发生的始基线上，在青春期出现症状，同正常乳房一样，受各种性激素的影响，呈周期性变化。"},"tr":{"name":"Çok sayıda göğüs","synonyms":["Polimasti","Aksesuar memeler"]}},"xrefs":[{"source":"ICD-10","code":"Q83.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"LB62","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1458532658"},{"source":"MONDO","code":"0015854","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0266010","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10049786","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":180170,"name":"Excess breast volume or number","classifications":[205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}