{"orpha":179490,"name":"Obesity due to congenital leptin resistance","type":"Etiological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-179490/","orphanet_url":"https://www.orpha.net/en/disease/detail/179490","names":{"fr":{"name":"Obésité due à une résistance congénitale à la leptine"},"de":{"name":"Adipositas durch kongenitale Leptin-Resistenz"},"es":{"name":"Obesidad por resistencia congénita a la leptina"},"it":{"name":"Obesità da resistenza congenita alla leptina"},"nl":{"name":"Obesitas door congenitale leptineresistentie"},"pt":{"name":"Obesidade por resistência congénita à leptina"},"pl":{"name":"Otyłość spowodowana wrodzona opornością na leptynę"},"cs":{"name":"Obezita způsobená vrozenou rezistencí na leptin"},"uk":{"name":"Ожиріння через вроджену резистентність до лептину"},"zh":{"name":"先天性瘦素抵抗所致肥胖"},"tr":{"name":"Doğumsal leptin direncine bağlı obezite"}},"xrefs":[{"source":"ICD-10","code":"E66.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"5B81.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"928534681"},{"source":"UMLS","code":"C5680486","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97978,"name":"Rare endocrine disease"},"parents":[{"orpha":98267,"name":"Genetic non-syndromic obesity","classifications":[156,193]}],"children":[{"orpha":179494,"name":"Obesity due to leptin receptor gene deficiency","type":"Etiological subtype"},{"orpha":71529,"name":"Obesity due to melanocortin 4 receptor deficiency","type":"Etiological subtype"},{"orpha":71526,"name":"Obesity due to pro-opiomelanocortin deficiency","type":"Etiological subtype"},{"orpha":71528,"name":"Obesity due to prohormone convertase I deficiency","type":"Etiological subtype"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}