{"orpha":178315,"name":"Undifferentiated embryonal sarcoma of the liver","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Embryonal sarcoma of the liver","UES","Undifferentiated sarcoma of the liver"],"definition":"Embryonal sarcoma of the liver is a rare primary malignant hepatic neoplasm of childhood of mesenchymal origin. It can rarely occur in adults. It is characterized by abdominal mass, right upper quadrant or epigastric pain, nausea, anorexia, intermittent fever or headache.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-178315/","orphanet_url":"https://www.orpha.net/en/disease/detail/178315","names":{"fr":{"name":"Sarcome embryonnaire indifférencié du foie","synonyms":["Sarcome embryonnaire isolé du foie","Sarcome non différencié du foie","UES"],"definition":"Le sarcome embryonnaire indifférencié du foie est une néoplasie hépatique primitive maligne et rare de l'enfant, d'origine mésenchymateuse. Il peut affecter les adultes dans de rares cas. Il est caractérisé par une masse abdominale, une douleur épigastrique ou dans le quadrant supérieur droit, des nausées, une anorexie, une fièvre ou une céphalée intermittentes."},"de":{"name":"Lebersarkom, embryonales undifferenziertes","synonyms":["Lebersarkom, embryonales","Lebersarkom, undifferenziertes","UES"],"definition":"Das embryonale Lebersarkom ist ein seltener primärer bösartiger Lebertumor des Kindesalters mit mesenchymalem Ursprung. Selten tritt er auch bei Erwachsenen auf. Er ist gekennzeichnet durch einen abdominellen Tumor, Schmerzen im rechten oberen Quadranten oder im Epigastrium, Übelkeit, Anorexie und intermittierendes Fieber oder Kopfschmerzen."},"es":{"name":"Sarcoma embrionario hepático indiferenciado","definition":"El sarcoma embrionario hepático es una neoplasia hepática maligna primaria poco frecuente de la infancia, de origen mesenquimal. Puede darse en adultos, aunque es poco frecuente. Se caracteriza por masa abdominal, dolor en el cuadrante superior derecho o epigástrico, náuseas, anorexia, fiebre intermitente o dolor de cabeza."},"it":{"name":"Sarcoma embrionale indifferenziato del fegato","synonyms":["Sarcoma embrionale del fegato","Sarcoma indifferenziato del fegato","UES"],"definition":"Il sarcoma embrionale del fegato è una neoplasia epatica maligna rara dell'infanzia, di origine mesenchimale. È raro nelle persone adulte. È caratterizzato da una massa addominale, dolore epigastrico o nel quadrante superiore destro, nausea, anoressia, febbre intermittente, cefalea."},"nl":{"name":"Niet-gedifferentieerd embryonaal sarcoom van lever","synonyms":["Embryonaal sarcoom van lever","Niet-gedifferentieerd sarcoom van lever","UES"],"definition":"Een zeldzaam primair maligne neoplasma van lever op kinderleeftijd van mesenchymale oorsprong. In zeldzame gevallen kan het voorkomen bij volwassenen. Het wordt gekenmerkt door abdominale mass, pijn in rechter bovenkwadrant van abdomen of epigastrische pijn, misselijkheid, anorexie, intermitterende koorts, of hoofdpijn."},"pt":{"name":"Sarcoma embrionário do fígado"},"pl":{"name":"Niezróżnicowany embrionalny mięsak wątroby","synonyms":["Embrionalny mięsak wątroby","Niezróżnicowany mięsak wątroby","UES"]},"cs":{"name":"Nediferencovaný embryonální sarkom jater","synonyms":["Embryonální sarkom jater","UES","Nediferencovaný sarkom jater"]},"uk":{"name":"Недиференційована ембріональна саркома печінки","synonyms":["Ембріональна саркома печінки","UES","Недиференційована саркома печінки"],"definition":"Embryonal sarcoma of the liver is a rare primary malignant hepatic neoplasm of childhood of mesenchymal origin. It can rarely occur in adults. It is characterized by abdominal mass, right upper quadrant or epigastric pain, nausea, anorexia, intermittent fever or headache."},"zh":{"name":"肝未分化胚胎性肉瘤","synonyms":["肝未分化肉瘤"],"definition":"肝脏未分化性胚胎肉瘤是一种罕见的儿童原发性肝脏间质性恶性肿瘤，成人发病率很低，其主要临床表现为腹部肿块、右上腹或上腹部疼痛、恶心、厌食、间歇性发热或头痛。"},"tr":{"name":"Karaciğerin farklılaşmamış embriyonal sarkomu","synonyms":["UES","Karaciğerin embriyonal sarkomu","Karaciğerin farklılaşmamış sarkomu"]}},"xrefs":[{"source":"ICD-10","code":"C22.4","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2B55.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"2144940292"},{"source":"MONDO","code":"0015795","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C2205345","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":306636,"name":"Rare tumor of liver and intrahepatic biliary tract","classifications":[183,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}