{"orpha":166308,"name":"Benign infantile focal epilepsy with midline spikes and waves during sleep","type":"Disease","group":"Disorder","status":"inactive","flags":["Deprecated entity"],"synonyms":["BIMSE"],"definition":null,"note":"This entity has been excluded from the Orphanet nomenclature of rare diseases and moved to Self-limited infantile epilepsy","url":"https://raremap.alftech.space/d/ORPHA-166308/","orphanet_url":"https://www.orpha.net/en/disease/detail/166308","names":{"fr":{"name":"Epilepsie focale infantile bénigne avec pointes-ondes centrales au cours du sommeil","synonyms":["BIMSE"]},"de":{"name":"Fokalepilepsie, benigne infantile, mit Midline-Spikes und Waves im Schlaf","synonyms":["BIMSE"]},"es":{"name":"Epilepsia focal benigna del lactante con puntas y ondas en línea media durante el sueño","synonyms":["BIMSE"]},"it":{"name":"Epilessia focale infantile benigna con punte e onde sulla linea mediana durante il sonno"},"nl":{"name":"Goedaardige infantiele focale epilepsie met pieken en golven in de middellijn tijdens de slaap","synonyms":["BIMSE"]},"pt":{"name":"Epilepsia focal benigna da infância com pontas e ondas da linha média durante o sono","synonyms":["BIMSE"]},"pl":{"name":"Łagodna dziecięca padaczka ogniskowa z iglicami i falami w linii pośrodkowej podczas snu","synonyms":["BIMSE"]},"cs":{"name":"Benigní infantilní fokální epilepsie se středočárovými hroty a vlnami ve spánku","synonyms":["BIMSE"]},"uk":{"name":"Доброякісна фокальна епілепсія раннього дитячого віку з центральною (центро-темпоральною) пік-хвильовою активністю під час сну","synonyms":["BIMSE"],"definition":"Benign infantile focal epilepsy with midline spikes and waves during sleep is a rare infantile epilepsy syndrome characterized by age of onset between 4 and 30 months, partial sporadic seizures presenting with motion arrest, staring, cyanosis and, less common, automatisms and lateralizing signs, and characteristic interictal sleep EEG changes consisting of a spike followed by a bell-shaped slow wave in the midline region."},"zh":{"name":"婴儿良性局灶性癫痫伴睡眠时中线棘波","synonyms":["BIMSE"],"definition":"良性婴儿局灶性癫痫伴睡眠时中线棘波，是一种罕见的婴幼儿癫痫综合征，其特征是发病年龄在4-30个月之间，呈部分散发性惊厥，表现为运动停止、凝视、紫绀，少数出现自动症和偏侧体征，发作间期睡眠脑电图改变为中线区域出现一个波峰，随后出现钟形慢波。"},"tr":{"name":"Uyku sırasında orta hat diken ve dalga ile seyreden selim infantil fokal epilepsi","synonyms":["BIMSE"]}},"xrefs":[{"source":"MONDO","code":"0015641","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4749346","qualifier":"E","icd_relation":null,"validated":true}],"associations":[{"type":"Moved to","orpha":306,"name":"Self-limited infantile epilepsy"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}