{"orpha":166291,"name":"Dirofilariasis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Dirofilariasis is a form of filariasis, caused by the filarial nematode of the genus <i>Dirofilaria</i> (including <i>Dirofilaria repens</i>, <i>Dirofilaria immitis</i>), which is transmitted by mosquitoes. The disease is characterized by the presence of subcutaneous nodules (or a conjunctival form that develops slowly and that can be painless to tender), edema and erythema at the site of parasite localization, a feeling of 'crawling' under the skin, and the ''Calabar'' swelling (similar to thatin loiasis. The latter may last a few days and recurrences are possible. Common localizations of dirofilaria are head and neck, most commonly in the periorbital region, the limbs and trunk.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-166291/","orphanet_url":"https://www.orpha.net/en/disease/detail/166291","names":{"fr":{"name":"Dirofilariose","definition":"La dirofilariose est une forme de filariose causée par le nématode filarien du genre <i>Dirofilaria</i> (incluant <i>Dirofilaria repens</i>, <i>Dirofilaria immitis</i>) transmis par différents types de moustiques. La maladie est caractérisée par la présence de nodules sous-cutanés (ou une forme conjonctivale se développant lentement, pouvant être indolore ou sensible), un oedème et un érythème au site de localisation du parasite, une sensation de reptation sous la peau, ainsi qu'un oedème de Calabar décrit dans la loase. Ce dernier peut durer quelques jours et des récidives sont possibles. Les localisations préférentielles de <i>Dirofilaria</i> sont la tête et le cou, le plus souvent dans la région péri-orbitale, les membres et le tronc."},"de":{"name":"Dirofilariose"},"es":{"name":"Dirofilariasis","definition":"La dirofilariasis es una forma de filariasis (véase este término) causada por el nematodo filarial del género <i>Dirofilaria</i> (que incluye a <i>Dirofilaria repens</i> y <i>Dirofilaria immitis</i>), que se transmite por picadura de mosquito. La enfermedad se caracteriza por la presencia de nódulos subcutáneos (o una forma conjuntiva que se desarrolla lentamente y puede ser indolora o producir sensibilidad), edemas y eritemas en la zona de localización del parásito, una sensación de ''reptación'' por debajo de la piel, y edema de Calabar (similar al de la loasis (véase este término)). Este último puede durar algunos días y es posible que haya recidivas. Las localizaciones habituales de la dirofilaria son la cabeza y el cuello, especialmente en la región periorbital, las extremidades y el tronco."},"it":{"name":"Dirofilariosi","definition":"La dirofilariosi è una forma di filariosi (si veda questo termine), causata da un nematode della famiglia delle <i>Filariidae</i> del genere <i>Dirofilaria</i> (che comprende <i>Dirofilaria repens</i> e <i>Dirofilaria immitis</i>), trasmessa dalle zanzare. La malattia è caratterizzata dalla presenza di noduli sottocutanei (o una forma congiuntivale a progressione lenta, che può essere indolore o dolente), edema ed eritema sul sito di inoculo del parassita, sensazione di distensione sotto la cute ed edema di Calabar (simile a quello descritto nella loiasi; si veda questo termine). Quest'ultimo può perdurare per alcuni giorni e può recidivare. I siti di inoculo più comuni della <i>Dirofilaria</i> sono la testa e il collo (più spesso nella regione periorbitale), gli arti e il tronco."},"nl":{"name":"Dirofilariase","definition":"Dirofilariasis is een vorm van filariasis (zie deze term), veroorzaakt door de filariale nematode van het genus <i>Dirofilaria</i> (inclusief <i>Dirofilaria repens</i>, <i>Dirofilaria immitis</i>), die overgedragen wordt door muggen. De ziekte wordt gekenmerkt door de aanwezigheid van subcutane nodules (of een conjunctivale vorm die traag ontwikkelt en die pijnloos tot gevoelig kan zijn), oedeem en erytheem op de plaats waar de parasiet zich bevindt, een gevoel van ''kruipen'' onder de huid, en de ''calabar''-zwelling (gelijkaardig als bij loiasis; zie deze term). Deze laatste kan enkele dagen aanhouden en recidieven zijn mogelijk. Algemene lokalisaties van dirofilaria zijn het hoofd en de nek, het vaakst in de periorbitale regio, de ledematen en de romp."},"pt":{"name":"Dirofilaríase"},"pl":{"name":"Dirofilarioza"},"cs":{"name":"Dirofilarióza"},"uk":{"name":"Дирофіляріоз","definition":"Dirofilariasis is a form of filariasis (see this term), caused by the filarial nematode of the genus <i>Dirofilaria</i> (including <i>Dirofilaria repens</i>, <i>Dirofilaria immitis</i>), which is transmitted by mosquitoes. The disease is characterized by the presence of subcutaneous nodules (or a conjunctival form that develops slowly and that can be painless to tender), edema and erythema at the site of parasite localization, a feeling of 'crawling' under the skin, and the ''Calabar'' swelling (similar to thatin loiasis (see this term). The latter may last a few days and recurrences are possible. Common localizations of dirofilaria are head and neck, most commonly in the periorbital region, the limbs and trunk."},"zh":{"name":"恶丝虫病","definition":"恶丝虫病是丝虫病(见该词条)的一种，由蚊虫传播的恶丝虫病属丝虫线虫(包括匍匐恶丝虫，犬恶丝虫)导致的疾病。该病的特征是皮下结节(或发展缓慢、无痛至触痛的结膜形状)，寄生虫寄生部位的水肿和红斑，皮肤下“爬行”感和卡拉巴肿(类似于罗阿丝虫病(见该词条))。后者导致的疾病可能会持续几天，并有可能复发。恶丝虫的常见部位是头部和颈部，最常见于眶周区、四肢和躯干。"},"tr":{"name":"Dirofilariyaz"}},"xrefs":[{"source":"ICD-10","code":"B74.8","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"1F66.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1349492056"},{"source":"MONDO","code":"0015636","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D004184","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0012602","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"11908","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10080290","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":2034,"name":"Filariasis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}