{"orpha":163908,"name":"OBSOLETE: Limbic encephalitis with LGI1 antibodies","type":"Disease","group":"Disorder","status":"inactive","flags":["Obsolete entity"],"synonyms":["OBSOLETE: Limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies"],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>Instead, consider using Autoimmune encephalitis","url":"https://raremap.alftech.space/d/ORPHA-163908/","orphanet_url":"https://www.orpha.net/en/disease/detail/163908","names":{"fr":{"name":"OBSOLETE : Encéphalite limbique avec anticorps anti-LGI1","synonyms":["OBSOLETE : Encéphalite limbique avec anticorps anti-leucine-rich glioma-inactivated 1"]},"de":{"name":"OBSOLET: Limbische Enzephalitis mit LGI1-Antikörpern","synonyms":["OBSOLET: VGKC-Komplex-Antikörper-Enzephalitis"]},"es":{"name":"OBSOLETO: Encefalitis límbica con anticuerpos LGI1","synonyms":["OBSOLETO: Encefalitis límbica con anticuerpos anti-proteína 1 inactivada del glioma rica en leucina"]},"it":{"name":"OBSOLETO: Encefalite limbica con anticorpi LGI1","synonyms":["OBSOLETO: Encefalite limbica con anticorpi anti-leucine-rich glioma-inactivated 1"]},"nl":{"name":"OBSOLEET: Limbische encefalitis met LGl1-antilichamen","synonyms":["OBSOLEET: Limbische encefalitis met leucine-rijke glioma-geïnactiveerde 1 antilichamen"]},"pt":{"name":"OBSOLETO: Encefalite límbica com anticorpos LGI1"},"pl":{"name":"NIEAKTUALNE: Zapalenie układu limbicznego z przeciwciałami LGI1","synonyms":["NIEAKTUALNE: Limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies"]},"cs":{"name":"NEAKTUÁLNÍ: Limbická encefalitida s pozitivitou anti-LGI1 protilátek","synonyms":["OBSOLETE: Limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies"]},"uk":{"name":"ЗАСТАРІЛО: Лімбічний енцефаліт з антитілами LGI1","synonyms":["ЗАСТАРІЛО: Лімбічний енцефаліт з лейцин-багатими антитілами до гліоми, інактивованими 1"]},"zh":{"name":"边缘脑炎伴LGI1抗体","synonyms":["抗富亮氨酸胶质瘤失活1蛋白抗体阳性边缘性脑炎"],"definition":"边缘叶脑炎伴LGI1抗体是一种罕见的神经免疫疾病，其特征是出现认知能力减退、精神障碍和惊厥(特别是面臂肌张力障碍惊厥)，且血清或脑脊液中可检测到LGI1抗体。患者可能会出现意识模糊、幻觉、发声、偏执、言不及义、攻击性表现和/或空间定向障碍，以及顽固性低钠血症。非副肿瘤最常见，但也有并存肿瘤的报导，如小细胞肺癌和胸腺瘤。"},"tr":{"name":"LGI1 antikorları ile seyreden limbik ensefalit","synonyms":["Lösin açısından zengin gliomla inaktive edilmiş 1 antikorlu limbik ensefalit"]}},"xrefs":[],"associations":[{"type":"Referred to","orpha":622014,"name":"Autoimmune encephalitis"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}