{"orpha":160148,"name":"Cap polyposis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Cap inflammatory polyposis","Eroded polypoid hyperplasia","Inflammatory myoglandular polyps","Polypoid prolapsing folds"],"definition":"A rare colorectal disease characterized by multiple inflammatory polyps that predominantly affect the rectosigmoid area and that manifests primarily as rectal bleeding with abnormal transit, constipation and diarrhea.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-160148/","orphanet_url":"https://www.orpha.net/en/disease/detail/160148","names":{"fr":{"name":"Cap polypose","synonyms":["Hyperplasie polypoïde érodée","Polype myoglandulaire inflammatoire"],"definition":"Maladie colorectale rare caractérisée par de multiples polypes inflammatoires affectant principalement la région rectosigmoïde et se manifestant par un saignement rectal, des troubles du transit, une constipation et une diarrhée."},"de":{"name":"Kappen-Polypose","synonyms":["Cap-Polypose","Polypen, entzündliche myoglanduläre","Polypoide Hyperplasie, erodierte"],"definition":"Eine seltene kolorektale Erkrankung, die durch multiple entzündliche Polypen gekennzeichnet ist, die vorwiegend den rektosigmoiden Bereich betreffen und sich vor allem durch rektale Blutungen mit abnormalem Transit, Verstopfung und Durchfall manifestieren."},"es":{"name":"Poliposis con capuchón","synonyms":["Hiperplasia polipoide erosionada","Pliegues polipoides prolapsados","Pliegues polipoides prolapsantes","Pólipos inflamatorios mioglandulares","Pólipos mioglandulares inflamatorios"],"definition":"Es una enfermedad colorrectal poco frecuente caracterizada por múltiples pólipos inflamatorios que afectan predominantemente al área rectosigmoidea y que se manifiesta inicialmente como un sangrado rectal con un tránsito anómalo, estreñimiento y diarrea."},"it":{"name":"Poliposi a cappuccio","definition":"La poliposi ''a cappuccio'' (CP) è una malattia rara del colon-retto, caratterizzata da polipi infiammatori multipli che si localizzano prevalentemente nella porzione retto-sigmoidea; i segni principali sono l'emorragia del retto associata ad alterazioni del transito, costipazione e diarrea."},"nl":{"name":"Cap polyposis","synonyms":["Geërodeerde polypoïde hyperplasie","Inflammatoire myoglandulaire poliepen","Polypoïde verzakkende vouwen"],"definition":"Een zeldzame colorectale aandoening gekarakteriseerd door multipele inflammatoire poliepen die vooral het rectosigmoïd treffen, en met rectaal bloedverlies met abnormale transit, constipatie en diarree als voornaamste manifestaties."},"pt":{"name":"Polipose Cap","definition":"A polipose cap é caracterizada por múltiplos pólipos inflamatórios colónicos característicos predominantemente localizados na porção retossigmóide do cólon (desde o recto até ao cólon distal)."},"pl":{"name":"Polipowatość z polipami typu \"cap\" (czapeczką fibrynową)","synonyms":["Eroded polypoid hyperplasia","Polipy zapalne mięsniowo-gruczołowe","Polypoid prolapsing folds"]},"cs":{"name":"Erodovaná polypoidní hyperplázie","synonyms":["Zánětlivé myoglandulární polypy","Prolabující polypoidní řasy"]},"uk":{"name":"Ковпачковий поліпоз","synonyms":["Запальний поліпоз кришечки","Ерозована поліпозна гіперплазія","Запальні міогландулярні поліпи","Поліпоїдні складки, що випинаються"],"definition":"A rare colorectal disease characterized by multiple inflammatory polyps that predominantly affect the rectosigmoid area and that manifests primarily as rectal bleeding with abnormal transit, constipation and diarrhea."},"zh":{"name":"帽状息肉病","synonyms":["炎性肌腺性息肉"],"definition":"一种罕见的结直肠疾病，其特征是多发性炎性息肉，主要影响直肠乙状结肠区域，主要表现为直肠出血，伴异常运输、便秘和腹泻。"},"tr":{"name":"Kapak polipozu","synonyms":["Polipoid sarkan kıvrımlar","Cap inflamatuar polipoz","Aşınmış polipoid hiperplazi","İnflamatuar miyoglandüler polipler"]}},"xrefs":[{"source":"ICD-10","code":"D12.6","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2E92.40","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1387262691"},{"source":"MONDO","code":"0015565","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4303971","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97935,"name":"Rare gastroenterologic disease"},"parents":[{"orpha":117569,"name":"Rare intestinal disease","classifications":[152]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult","Childhood","Elderly"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":67.0,"area":"Worldwide","status":"Validated","source":"24949613[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET_24949613[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-10-17","source":"23416507[PMID]_22333383[PMID]","terms":[{"hpo":"HP:0200063","label":"Colorectal polyposis","frequency":"Obligate (100%)","criteria":null},{"hpo":"HP:0002027","label":"Abdominal pain","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002582","label":"Atrophic gastritis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002019","label":"Constipation","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002573","label":"Hematochezia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0003270","label":"Abdominal distention","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002014","label":"Diarrhea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001824","label":"Weight loss","frequency":"Frequent (79-30%)","criteria":null}]}}