{"orpha":157823,"name":"Klüver-Bucy syndrome","type":"Clinical syndrome","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare neurologic disease characterized by visual agnosia, hyperorality (strong tendency to examine objects orally), hypermetamorphosis (described as the irresistible impulse to notice and react to everything within sight), hypersexuality, changes in dietary habits and hyperphagia, placidity, and amnesia, due to bilateral lesions of the temporal lobe including the hippocampus and amygdala.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-157823/","orphanet_url":"https://www.orpha.net/en/disease/detail/157823","names":{"fr":{"name":"Syndrome de Klüver-Bucy","definition":"Maladie neurologique rare caractérisée par une agnosie visuelle, une hyperoralité (forte tendance à explorer les objets avec la bouche), une hypermétamorphose (décrite comme l'impulsion irrésistible à remarquer et à réagir à tout ce qui se trouve à portée de vue), une hypersexualité, des changements dans les habitudes alimentaires et une hyperphagie, une placidité et une amnésie, dues à des lésions bilatérales du lobe temporal ainsi que de l'hippocampe et l'amygdale."},"de":{"name":"Klüver-Bucy-Syndrom","definition":"Eine seltene neurologische Erkrankung, die durch visuelle Agnosie, Hyperoralität (starke Tendenz, Objekte oral zu untersuchen), Hypermetamorphose (beschrieben als unwiderstehlicher Impuls, alles in Sichtweite zu bemerken und darauf zu reagieren), Hypersexualität, veränderte Ernährungsgewohnheiten und Hyperphagie, Gelassenheit und Amnesie gekennzeichnet ist und auf bilaterale Läsionen des Schläfenlappens einschließlich des Hippocampus und der Amygdala zurückzuführen ist."},"es":{"name":"Síndrome de Klüver-Bucy","definition":"Es una enfermedad neurológica poco frecuente caracterizada por agnosia visual, hiperoralidad (fuerte tendencia a examinar objetos por vía oral), hipermetamorfosis (descrita como el impulso irresistible a observar y reaccionar con todo lo que está a la vista), hipersexualidad, cambios en los hábitos alimentarios e hiperfagia, placidez y amnesia, debido a lesiones bilaterales del lóbulo temporal que incluyen el hipocampo y la amígdala."},"it":{"name":"Sindrome di Klüver-Bucy","definition":"Si tratta di una malattia neurologica rara, caratterizzata da agnosia visiva, iperoralità (forte tendenza ad esaminare gli oggetti con la bocca), ipermetamorfosi (impulso irresistibile a notare e reagire a tutto ciò che si trova a portata della vista), ipersessualità, cambiamento delle abitudini alimentari e iperfagia, placidità e amnesia, secondarie alle lesioni bilaterali del lobo temporale (ippocampo e amigdala)."},"nl":{"name":"Syndroom van Klüver-Bucy","definition":"Een zeldzame neurologische aandoening, gekarakteriseerd door visuele agnosie, hyperoraliteit (sterke neiging om objecten oraal te onderzoeken), hypermetamorfose (beschreven als onweerstaanbare drang om alles in het zicht op te merken en er op te reageren), hyperseksualiteit, veranderingen van eetgewoonten en hyperfagie, kalmte, en amnesie, te wijten aan bilaterale laesies van temporaalkwab, inclusief hippocampus en amygdala."},"pt":{"name":"Síndrome de Klüver-Bucy"},"pl":{"name":"Zespół Klüvera i Bucy'ego"},"cs":{"name":"Klüverův-Bucyho syndrom","synonyms":["Klüver-Bucyho syndrom"]},"uk":{"name":"Синдром Клювера-Бюсі","definition":"A rare neurologic disease characterized by visual agnosia, hyperorality (strong tendency to examine objects orally), hypermetamorphosis (described as the irresistible impulse to notice and react to everything within sight), hypersexuality, changes in dietary habits and hyperphagia, placidity, and amnesia, due to bilateral lesions of the temporal lobe including the hippocampus and amygdala."},"zh":{"name":"Kl³ver-Bucy 综合征","definition":"一种罕见的神经系统疾病，其特征是视觉失认、口部过度活动（具有口部尝试物体的强烈倾向）、思维变化过速（被描述为对所看到的一切事物都有不可抗拒的注意和反应冲动）、性欲亢进、饮食习惯改变和饮食过多，以及包含海马和杏仁核的双侧颞叶病边所导致的平静和健忘。"},"tr":{"name":"Klüver-Bucy sendromu"}},"xrefs":[{"source":"ICD-10","code":"G04.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0005817","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D020232","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0270707","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6840","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10066431","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":98033,"name":"Rare neurologic disease with psychiatric involvement","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}