{"orpha":1482,"name":"Gonococcal conjunctivitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare disorder of the anterior segment of the eye caused by <i>Neisseria gonorrhoeae</i>, characterized by a severe mucopurulent conjunctivitis associated with lid edema, often also with localized lymphadenopathy. It may be complicated by uveitis or keratitis which can eventually lead to corneal perforation. The disease most often occurs in teenagers and young adults with a male predominance, while infections are much less common in newborns, where they are typically bilateral.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-1482/","orphanet_url":"https://www.orpha.net/en/disease/detail/1482","names":{"fr":{"name":"Conjonctivite gonococcique","definition":"Maladie rare du segment antérieur de l'oeil causé par <i>Neisseria gonorrhoeae</i>, caractérisée par une conjonctivite mucopurulente sévère associée à un oedème des paupières, souvent accompagnée d'une lymphadénopathie localisée. Elle peut se compliquer d'une uvéite ou d'une kératite qui peut éventuellement entraîner une perforation de la cornée. La maladie se manifeste le plus souvent chez les adolescents et les jeunes adultes avec une prédominance masculine, tandis que les infections sont beaucoup moins fréquentes chez les nouveau-nés, auquel cas elles sont généralement bilatérales."},"de":{"name":"Gonokokkenkonjunktivitis","synonyms":["Gonoblennorrhoe"],"definition":"Eine seltene Erkrankung des vorderen Augenabschnitts, die durch <i>Neisseria gonorrhoeae</i> verursacht wird und durch eine schwere mukopurulente Konjunktivitis in Verbindung mit einem Lidödem gekennzeichnet ist, oft auch mit lokalisierter Lymphadenopathie. Sie kann durch eine Uveitis oder Keratitis kompliziert werden, die schließlich zu einer Perforation der Hornhaut führen kann. Die Krankheit tritt am häufigsten bei Teenagern und jungen Erwachsenen auf, wobei Männer überwiegen, während Infektionen bei Neugeborenen viel seltener vorkommen und in der Regel beidseitig sind."},"es":{"name":"Conjuntivitis gonocócica","definition":"Es un trastorno poco frecuente del segmento anterior ocular causado por <i>Neisseria gonorrhoeae</i>, caracterizado por una grave conjuntivitis mucopurulenta asociada a edema palpebral y, con frecuencia, también a una linfadenopatía localizada. Puede complicarse por una uveítis o una queratitis, que posteriormente pueden derivar en una perforación corneal. La enfermedad aparece con mayor frecuencia en adolescentes y en adultos jóvenes con un predominio masculino, mientras que las infecciones son mucho menos frecuentes en los neonatos, siendo típicamente bilaterales."},"it":{"name":"Congiuntivite gonococcica","definition":"Si tratta di una malattia rara del segmento anteriore dell'occhio, causata da <i>Neisseria gonorrhoeae</i>, e caratterizzata da una grave congiuntivite mucopurulenta associata ad edema della palpebra, spesso con linfoadenopatia localizzata. Può associarsi a complicanze, quali l'uveite o la cheratite, che possono causare la perforazione della cornea. In genere la malattia colpisce gli adolescenti e i giovani adulti ed è più frequente nei maschi. Nei neonati le infezioni sono in genere bilaterali e molto meno comuni."},"nl":{"name":"Gonokokken-conjunctivitis","definition":"Een zeldzame aandoening van voorste oogsegment, veroorzaakt door <i>Neisseria gonorrhoeae</i>, en gekarakteriseerd door ernstige mucopurulente conjunctivitis geassocieerd met oedeem van ooglid, en vaak ook met gelokaliseerde lymfadenopathie. Het kan gecompliceerd worden door uveïtis of keratitis, wat uiteindelijk kan leiden tot perforatie van cornea. De ziekte komt het vaakst voor bij tieners en jonge volwassenen, en meer bij mannen dan bij vrouwen, terwijl infecties veel minder voorkomen bij neonaten, bij wie ze doorgaans bilateraal zijn."},"pt":{"name":"Conjuntivite gonocócica"},"pl":{"name":"Rzeżączkowe zapalenie spojówek"},"cs":{"name":"Gonoroická konjunktivitida","synonyms":["Gonokoková konjunktivitida"]},"uk":{"name":"Гонококовий конюнктивіт","definition":"A rare disorder of the anterior segment of the eye caused by <i>Neisseria gonorrhoeae</i>, characterized by a severe mucopurulent conjunctivitis associated with lid edema, often also with localized lymphadenopathy. It may be complicated by uveitis or keratitis which can eventually lead to corneal perforation. The disease most often occurs in teenagers and young adults with a male predominance, while infections are much less common in newborns, where they are typically bilateral."},"zh":{"name":"淋菌性结膜炎"},"tr":{"name":"Gonokokal konjuktivit"}},"xrefs":[{"source":"ICD-10","code":"A54.3+","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"H13.1*","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"1A72.4","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"884042621"},{"source":"MONDO","code":"0015455","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D009878","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5779547","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"2546","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":519280,"name":"Rare conjunctivitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Prevalence at birth","qualification":"Value and class","class":"1-5 / 10 000","value":30.0,"area":"United States","status":"Validated","source":"31855399[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}