{"orpha":141327,"name":"OBSOLETE: Orofaciodigital syndrome type 12","type":"Malformation syndrome","group":"Disorder","status":"inactive","flags":["Obsolete entity"],"synonyms":["OBSOLETE: Moran-Barroso syndrome","OBSOLETE: OFD12","OBSOLETE: Oral-facial-digital syndrome type 12"],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>Instead, consider using Orofaciodigital syndrome","url":"https://raremap.alftech.space/d/ORPHA-141327/","orphanet_url":"https://www.orpha.net/en/disease/detail/141327","names":{"fr":{"name":"OBSOLETE : Syndrome oro-facio-digital type 12","synonyms":["OBSOLETE : OFD12","OBSOLETE : Syndrome de Moran-Barroso"]},"de":{"name":"OBSOLET: Oro-fazio-digitales Syndrom Typ 12","synonyms":["OBSOLET: Moran-Barroso-Syndrom","OBSOLET: OFD12","OBSOLET: Oral-fazial-digitales Syndrom Typ 12"]},"es":{"name":"OBSOLETO: Síndrome orofaciodigital tipo 12","synonyms":["OBSOLETO: Síndrome oro-facio-digital tipo 12","OBSOLETO: OFD12","OBSOLETO: Síndrome de Moran-Barroso"]},"it":{"name":"OBSOLETO: Sindrome orofaciodigitale tipo 12","synonyms":["OBSOLETO: OFD12","OBSOLETO: Sindrome di Moran-Barroso","OBSOLETO: Sindrome oro-facio-digitale tipo 12","OBSOLETO: Sindrome oro-facio-digitale, tipo 12","OBSOLETE: Sindrome di Moran-Barroso"]},"nl":{"name":"OBSOLEET: Orofaciodigitaal syndroom type 12","synonyms":["OBSOLEET: OFD12","OBSOLEET: Oraal-faciaal-digitaal syndroom type 12","OBSOLEET: Syndroom van Moran-Barroso"]},"pt":{"name":"OBSOLETO: Síndrome orofaciodigital tipo 12"},"pl":{"name":"NIEAKTUALNE: Zespół ustno-twarzowo-palcowy typu 12","synonyms":["NIEAKTUALNE: OFD12"]},"cs":{"name":"NEAKTUÁLNÍ: Orofaciodigitální syndrom, typ 12","synonyms":["NEAKTUÁLNÍ: OFD12"]},"uk":{"name":"ЗАСТАРІЛО: Орофаціодигітальний синдром, тип 12","synonyms":["ЗАСТАРІЛО: Синдром Морана-Баррозу","ЗАСТАРІЛО: OFD12","ЗАСТАРІЛО: Орально-лицево-пальцевий синдром, тип 12"]},"zh":{"name":"口面指综合征12型","synonyms":["口-面-指综合征12型"],"definition":"口面指综合征12型是口腔颌面部综合征的一种罕见亚型，散发，其特征是心脏（中隔肥大）和中枢神经系统异常（脊髓脊膜膨出、西尔维于斯导水管畸形、胼胝体发育不全、蚓体发育不全），此外还有口腔、面部和指趾畸形（牙龈系带、二裂舌、多生牙、大头畸形、眼距过宽、手部轴前轴后性多指畸形、足部轴前多趾畸形和马蹄内翻足）。也与骨骼异常相关，如短胫骨和中央Y形掌骨，也有关联。"},"tr":{"name":"Orofasiyodijital sendrom tip 12","synonyms":["OFD12","Moran-Barroso sendromu","Oral-fasiyal-dijital sendromu tip 12"]}},"xrefs":[],"associations":[{"type":"Referred to","orpha":140997,"name":"Orofaciodigital syndrome"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}