{"orpha":141083,"name":"Nasolacrimal duct cyst","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["Dacryocele","Dacryocystocele","Nasolacrimal mucocele"],"definition":"Nasolacrimal duct cyst describes a unilateral or bilateral congenital cyst of the nasolacrimal duct, which is almost always associated with dacryocystocele, presenting most commonly at birth or a few weeks of age (but rarely presenting in adulthood) as a benign, grayish blue mass in the inferomedial canthus or in the nasal cavity, that can cause epiphora, dacryocystitis (inflammation of the lacrimal sac) and nasal obstruction. It is more commonly reported in females.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-141083/","orphanet_url":"https://www.orpha.net/en/disease/detail/141083","names":{"fr":{"name":"Kyste lacrymo-nasal","synonyms":["Mucocèle lacrymo-nasal","Dacryocystocèle","Dacryocèle"],"definition":"Le kyste lacrymo-nasal est un kyste congénital uni- ou bilatéral du canal nasolacrymal, presque toujours associé à un dacryocystocèle. Il se manifeste le plus souvent à la naissance ou au cours des premières semaines de vie (rarement à l'âge adulte) par une masse bénigne bleue-gris dans le canthus inféro-médial ou dans la cavité nasale, et peut causer un larmoiement, une dacryocystite (inflammation du sac lacrymal) et une occlusion nasale. Il est rapporté plus souvent chez les individus féminins."},"de":{"name":"Tränenwegzyste","synonyms":["Dakryozele","Dakryozystozele","Mukozele der Tränenwege"]},"es":{"name":"Quiste del conducto nasolagrimal","synonyms":["Dacriocele","Dacriocistocele","Mucocele nasolagrimal"],"definition":"El quiste del conducto nasolagrimal describe un quiste congénito uni- o bilateral del conducto nasolagrimal, casi siempre asociado a un dacriocistocele, que se presenta con mayor frecuencia al nacimiento o a las pocas semanas de vida (pero que raramente se desarrolla en la edad adulta) como una masa benigna de color azul grisáceo en el canto inferomedial o en la cavidad nasal, y que puede causar epífora, dacriocistitis (inflamación del saco lagrimal) y obstrucción nasal. Es más frecuente en mujeres."},"it":{"name":"Cisti del dotto nasolacrimale","synonyms":["Dacriocele","Dacriocistocele","Mucocele nasolacrimale"],"definition":"La cisti del dotto nasolacrimale è una cisti congenita monolaterale o bilaterale del dotto nasolacrimale, quasi sempre associata a dacriocistocele, che esordisce di solito alla nascita o poche settimane dopo la nascita (raramente in età adulta), sotto forma di una massa blu-grigiastra benigna localizzata nel canto infero-mediale o nella cavità nasale, che può causare epifora, dacriocistite (infiammazione del sacco lacrimale) e ostruzione nasale. È più comune nelle femmine."},"nl":{"name":"Cyste van ductus nasolacrimalis","synonyms":["Dacryocele","Dacryocystocele","Nasolacrimale mucocele"],"definition":"Cyste van het nasolacrimaal kanaal beschrijft een unilaterale of bilaterale congenitale cyste van het nasolacrimaal kanaal die bijna altijd geassocieerd is met dacryocystostele en zich doorgaans manifesteert bij de geboorte of enkele weken na de geboorte (maar zelden in de volwassenheid) als een goedaardige, grijsblauwe massa in de inferomediale canthus of in de neusholte, die kan leiden tot epifora, dacryocystitis (ontsteking van de traanzak) en nasale obstructie. Het wordt meer gerapporteerd bij vrouwen."},"pt":{"name":"Quisto do ducto nasolacrimal"},"pl":{"name":"Torbiel przewodu nosowo-łzowego","synonyms":["Torbiel worka łzowego","Wrodzona torbiel śluzowa przewodu nosowo-łzowego"]},"cs":{"name":"Cysta ductus nasolacrimalis","synonyms":["Dakryokéla","Dakryocystokéla","Mukokéla slzovodu"]},"uk":{"name":"Кіста носослізної протоки","synonyms":["Дакріоцеле","Дакріоцистоцеле","Носослізне мукоцеле"],"definition":"Nasolacrimal duct cyst describes a unilateral or bilateral congenital cyst of the nasolacrimal duct, which is almost always associated with dacryocystocele, presenting most commonly at birth or a few weeks of age (but rarely presenting in adulthood) as a benign, grayish blue mass in the inferomedial canthus or in the nasal cavity, that can cause epiphora, dacryocystitis (inflammation of the lacrimal sac) and nasal obstruction. It is more commonly reported in females."},"zh":{"name":"鼻泪管囊肿","synonyms":["鼻泪粘液囊肿"],"definition":"鼻泪管囊肿指单侧或双侧先天性鼻泪管囊肿，常伴泪囊突出，出生或数周大时最常见（成人期很罕见），表现为位于下眼角或鼻腔内的灰蓝色良性肿块，可能导致溢泪、泪囊炎（泪囊炎症）和鼻塞。女性中更常见。"},"tr":{"name":"Nazolakrimal kanal kisti","synonyms":["Dakriyosel","Dakriyosistosel","Nazolakrimal mukosel"]}},"xrefs":[{"source":"ICD-10","code":"H04.6","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"LA14.12","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"609107581"},{"source":"MONDO","code":"0015387","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5575612","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19944","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":98605,"name":"Lacrimal drainage system anomaly","classifications":[147,189]},{"orpha":156246,"name":"Nose and cavum anomaly","classifications":[147,200]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult","Infancy","Neonatal"],"prevalence":[{"type":"Prevalence at birth","qualification":"Value and class","class":"1-5 / 10 000","value":25.7,"area":"United States","status":"Validated","source":"21035068[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2021-11-22","source":"26724215[PMID]_22852130[PMID]_25825046[PMID]_32714680[PMID]","terms":[{"hpo":"HP:0030829","label":"Abnormal breath sound","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:3000066","label":"Abnormal lacrimal sac morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000620","label":"Dacryocystitis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0009926","label":"Epiphora","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030215","label":"Inappropriate crying","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001742","label":"Nasal congestion","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000579","label":"Nasolacrimal duct obstruction","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012763","label":"Paroxysmal dyspnea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000646","label":"Amblyopia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100658","label":"Cellulitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007717","label":"Chronic irritative conjunctivitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025612","label":"Corneal astigmatism","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030752","label":"Dacryocystocele","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004411","label":"Deviated nasal septum","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007651","label":"Ectropion of lower eyelids","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004885","label":"Episodic respiratory distress","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030864","label":"Intercostal retractions","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0045025","label":"Narrow palpebral fissure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0200026","label":"Ocular pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100539","label":"Periorbital edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002033","label":"Poor suck","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002719","label":"Recurrent infections","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025337","label":"Red eye","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0010307","label":"Stridor","frequency":"Occasional (29-5%)","criteria":null}]}}