{"orpha":141061,"name":"Commissural lip fistula","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare otorhinolaryngological malformation characterized by a unilateral or bilateral fistula located at the corner of the mouth, where the vermillion border of the upper lip meets that of the lower lip. The lesion is lined by labial mucosa. It is potentially susceptible to infection.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-141061/","orphanet_url":"https://www.orpha.net/en/disease/detail/141061","names":{"fr":{"name":"Fistule de la commissure labiale","definition":"Malformation otorhinolaryngologique rare, caractérisée par une fistule unilatérale ou bilatérale située à la commissure des lèvres, à la jonction du bord vermillon de la lèvre supérieure et de la lèvre inférieure. La lésion est tapissée de muqueuse labiale et potentiellement sensible aux infections."},"de":{"name":"Lippenfistel, kommissurale","definition":"Eine seltene otorhinolaryngologische Fehlbildung, die durch eine ein- oder beidseitige Fistel am Mundwinkel gekennzeichnet ist, wo der Lippenrotrand der Oberlippe auf den der Unterlippe trifft. Die Läsion ist von der Lippenschleimhaut ausgekleidet. Sie ist potenziell anfällig für Infektionen."},"es":{"name":"Fístula en la comisura del labio","definition":"Es una malformación otorrinolaringológica poco frecuente caracterizada por una fístula uni- o bilateral localizada en la comisura de la boca, en la unión del borde bermellón del labio superior y del labio inferior. La lesión está revestida por mucosa labial y es potencialmente susceptible a la infección."},"it":{"name":"Fistola della commissura labiale","definition":"Si tratta di una malformazione rara di interesse otorinolaringoiatrico, caratterizzata da una fistola mono- o bilaterale localizzata nel'angolo della bocca, alla giunzione tra la porzione mucosa del labbro superiore e del labbro inferiore. La lesione è rivestita da mucosa labiale e può andare incontro ad infezione."},"nl":{"name":"Commissurale lipfistel","definition":"Een zeldzame otorinolaryngologische malformatie, gekenmerkt door een unilaterale of bilaterale fistel gesitueerd in de mondhoek, waar vermiljoen van bovenlip samenkomt met vermiljoen van onderlip. The laesie is bekleed met lipslijmvlies. Het is mogelijk vatbaar voor infectie."},"pt":{"name":"Fístula da comissura do lábio","definition":"Malformação otorrinolaringológica rara caracterizada por fístula unilateral ou bilateral localizada no canto da boca, onde o vermelhão do lábio superior encontra o lábio inferior. A lesão é revestida por mucosa labial. É potencialmente suscetível à infeção."},"pl":{"name":"Przetoka spoidła wargi"},"cs":{"name":"Komisurální píštěl rtu"},"uk":{"name":"Комісуральна нориця губи","definition":"A rare otorhinolaryngological malformation characterized by a unilateral or bilateral fistula located at the corner of the mouth, where the vermillion border of the upper lip meets that of the lower lip. The lesion is lined by labial mucosa. It is potentially susceptible to infection."},"zh":{"name":"口角瘘管"},"tr":{"name":"Komisüral dudak fistülü"}},"xrefs":[{"source":"ICD-10","code":"Q38.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA5Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"27017896"},{"source":"MONDO","code":"0015381","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680634","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19939","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":155835,"name":"Cysts and fistulae of the face and oral cavity","classifications":[147,200]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}