{"orpha":137602,"name":"Corneal endotheliitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare corneal disorder characterized by inflammation of the corneal endothelium with corneal edema, keratic precipitates, mild to moderate anterior chamber reaction, and subsequent visual disturbances. It is often associated with increased intraocular pressure. Based on the distribution of the lesions, a linear, sectorial, disciform, and diffuse form can be distinguished.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-137602/","orphanet_url":"https://www.orpha.net/en/disease/detail/137602","names":{"fr":{"name":"Endothélite herpétique","definition":"Maladie cornéenne rare caractérisée par une endothélite avec oedème de cornée, des précipités kératiques, une réaction inflammatoire légère à modérée de la chambre antérieure donnant lieu à des troubles visuels. Elle est souvent associée à une augmentation de la pression intraoculaire. Suivant la répartition des lésions, on peut distinguer des formes linéaire, sectorielle, disciforme et diffuse."},"de":{"name":"Endotheliitis","definition":"Eine seltene Hornhauterkrankung, die durch eine Entzündung des Hornhautendothels mit Hornhautödem, keratischem Niederschlag, leichter bis mittelschwerer Vorderkammerreaktion und nachfolgenden Sehstörungen gekennzeichnet ist. Sie ist häufig mit einem erhöhten Augeninnendruck verbunden. Anhand der Verteilung der Läsionen lassen sich eine lineare, sektorielle, scheibenförmige und diffuse Form unterscheiden."},"es":{"name":"Endotelitis","definition":"Es un trastorno corneal poco frecuente caracterizado por inflamación del endotelio corneal con edema corneal, precipitados queráticos, reacción de la cámara anterior de leve a moderada y alteraciones visuales posteriores. A menudo se asocia con un aumento de la presión intraocular. En base a la distribución de las lesiones se distinguen varias formas: lineal, sectorial, disciforme y difusa."},"it":{"name":"Endotelite","definition":"Si tratta di una malattia rara della cornea, caratterizzata dall'infiammazione dell'endotelio corneale, associata ad edema, precipitati cheratici, reazione lieve-moderata della camera anteriore e conseguenti deficit visivi. Spesso si associa ad un aumento della pressione intraoculare. In base alla distribuzione delle lesioni, la malattia si differenzia nelle forme lineare, settoriale, disciforme o diffusa."},"nl":{"name":"Endotheliitis","definition":"Een zeldzame aandoening van cornea, gekarakteriseerd door inflammatie van endotheel van cornea met corneaoedeem, keratitische precipitaten, milde tot matige reactie van voorste oogkamer, en daaropvolgend visuele stoornissen. Deze aandoening is vaak geassocieerd met verhoogde intraoculaire druk. Op basis van de distributie van laesies wordt een lineaire, sectorale, disciforme, en diffuse vorm onderscheiden."},"pt":{"name":"Endotelite"},"pl":{"name":"Zapalenie śródbłonka"},"cs":{"name":"Endoteliitida"},"uk":{"name":"Ендотеліїт рогівки","definition":"A rare corneal disorder characterized by inflammation of the corneal endothelium with corneal edema, keratic precipitates, mild to moderate anterior chamber reaction, and subsequent visual disturbances. It is often associated with increased intraocular pressure. Based on the distribution of the lesions, a linear, sectorial, disciform, and diffuse form can be distinguished."},"zh":{"name":"内皮炎","definition":"内皮炎是一种罕见的角膜疾病，其特征是角膜内皮细胞发炎，角膜水肿，角膜沉淀，轻度到中度前房反应，以及随后的视觉障碍。它常与眼压升高有关。根据病变的分布，可以区分为线状、扇形、盘状和弥漫性。"},"tr":{"name":"Endotelit"}},"xrefs":[{"source":"ICD-10","code":"H16.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9A70.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"677984188"},{"source":"MONDO","code":"15292","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0423262","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19880","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10062621","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":519278,"name":"Infective keratitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}