{"orpha":137593,"name":"Infectious epithelial keratitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Infectious epithelial keratitis is a rare, potentially sight-threatening, acquired ocular disease chracterized by corneal epithelium inflammation resulting from viral (mainly Herpes Simplex virus), bacterial, fungic or protist infection, manifesting with variable symptoms, such as conjunctival hyperemia, lacrimation, rapid onset of pain, blurred vision and/or photophobia, depending on the causative agent.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-137593/","orphanet_url":"https://www.orpha.net/en/disease/detail/137593","names":{"fr":{"name":"Kératite épithéliale d'origine infectieuse","definition":"Maladie oculaire acquise, rare et potentiellement dangereuse pour la vue, caractérisée par une inflammation de l'épithélium cornéen résultant d'une infection virale (principalement à <i>Herpes Simplex</i>), bactérienne, fongique ou protiste, se manifestant par des symptômes qui varient en fonction de l'agent causal, à savoir hyperémie conjonctivale, larmoiement, apparition soudaine de la douleur, vision floue et/ou photophobie."},"de":{"name":"Keratitis, epitheliale infektiöse"},"es":{"name":"Queratitis epitelial infecciosa","definition":"La queratitis epitelial infecciosa es una enfermedad ocular adquirida y poco frecuente que pone en riesgo la visión. Está caracterizada por inflamación del epitelio corneal como resultado de una infección vírica (principalmente por el virus del herpes simple), bacteriana, fúngica o protista. Se manifiesta con síntomas variables, según el agente causal, tales como hiperemia conjuntival, lagrimeo, dolor de aparición repentina, visión borrosa y/o fotofobia."},"it":{"name":"Cheratite epiteliale infettiva","definition":"La cheratite epiteliale infettiva è una malattia oculare acquisita rara, che può causare cecità. È caratterizzata dall'infiammazione dell'epitelio della cornea, secondaria alle infezioni virali (soprattutto da herpes simplex), batteriche, fungine o da protisti. Si manifesta con iperemia della congiuntiva, lacrimazione, dolore ad esordio rapido, annebbiamento della vista e/o fotofobia, a seconda dell'agente scatenante."},"nl":{"name":"Infectieuze epitheliale keratitis","definition":"Infectieuze epitheliale keratitis is een zeldzame, verworven oogziekte die mogelijk het gezichtsvermogen bedreigt, die gekenmerkt wordt door inflammatie van het epitheel van het hoornvlies ten gevolge van infectie met een virus (voornamelijk herpes-simplexvirus), bacterie, schimmel of protist, en die zich manifesteert met variabele symptomen, zoals conjunctivale hyperemie, lacrimatie, snelle aanvang van pijn, wazig zicht en/of fotofobie, afhankelijk van het causale agens."},"pt":{"name":"Queratite infeciosa epitelial"},"pl":{"name":"Zakaźne nabłonkowe zapalenie rogówki","definition":"*Zakaźne nabłonkowe zapalenie rogówki jest rzadką, potencjalnie zagrażającą widzeniu, nabytą chorobą oczu, która charakteryzuje się stanem zapalnym nabłonka rogówki, który rozwija się w wyniku zakażenia wirusowego (głównie wirusem opryszczki pospolitej), bakteryjnej, grzybiczej lub pierwotniakowej. Charakteryzuje się, w zależności od czynnika przyczynowego, zmiennymi objawami, w tym przekrwieniem spojówek, łzawieniem, bólem o nagłym początku, niewyraźnym widzenie, i/lub światłowstrętem.inf brsup inf brsup"},"cs":{"name":"Infekční epiteliální keratitida"},"uk":{"name":"Інфекційний епітеліальний кератит","definition":"Infectious epithelial keratitis is a rare, potentially sight-threatening, acquired ocular disease chracterized by corneal epithelium inflammation resulting from viral (mainly Herpes Simplex virus), bacterial, fungic or protist infection, manifesting with variable symptoms, such as conjunctival hyperemia, lacrimation, rapid onset of pain, blurred vision and/or photophobia, depending on the causative agent."},"zh":{"name":"感染性上皮性角膜炎","definition":"感染上皮角膜炎是一种罕见的、可能影响视力的获得性眼部疾病，以由病毒(主要是单纯疱疹病毒),细菌、真菌或原生生物感染所致的角膜上皮炎症为特征，表现出各种政治，如结膜充血、流泪，迅速出现疼痛、视力模糊和/或畏光,这取决于病原体。"},"tr":{"name":"Bulaşıcı epitel keratit"}},"xrefs":[{"source":"ICD-10","code":"H16.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1F00.10","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"2103923676"},{"source":"MONDO","code":"0015289","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4749790","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":519278,"name":"Infective keratitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}