{"orpha":129,"name":"Pseudopelade of Brocq","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Pseudo-pelade of Brocq is a rare hair abnormality characterized by onset in adulthood of soft, irregular, flesh-toned patches of alopecia primarily in the parietal and vertex portions of the scalp, without follicular hyperkeratosis or perifollicular inflammation.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-129/","orphanet_url":"https://www.orpha.net/en/disease/detail/129","names":{"fr":{"name":"Pseudo-pelade de Brocq","definition":"La pseudo-pelade de Brocq est une forme d'alopécie cicatricielle en plaques qui s'étend lentement et progressivement, mais sans folliculite évidente. Les signes cliniques et histologiques peuvent ressembler à ceux du lichen plan. L'étiologie est inconnue. La phase d'extension est marquée par un cuir chevelu inflammatoire rosé et par une infiltration lymphocytaire péripilaire. Par la suite, les follicules sont détruits, le derme est sclérosé et l'épiderme est atrophique."},"de":{"name":"Pseudopelade Brocq","definition":"Die Pseudo-Pelade Brocq ist eine seltene Haaranomalie mit Beginn im Erwachsenenalter. Kennzeichen sind weiche, unregelmäßig begrenzte, fleischfarbene Alopezie-Areale an der Kopfhaut, vor allem an Schläfen und Scheitel, ohne follikuläre Hyperkeratose oder perifollikuläre Entzündung."},"es":{"name":"Pseudopelada de Brocq","definition":"La pseudopelada de Brocq es una anomalía del pelo poco frecuente que se caracteriza por la aparición en la edad adulta de parches de alopecia blandos, irregulares y de color carne, principalmente en las regiones parietal y vértice del cuero cabelludo, sin hiperqueratosis folicular o inflamación perifolicular."},"it":{"name":"Pseudoalopecia areata di Brocq","definition":"La pseudo-alopecia di Brocq è un'anomalia rara dei capelli, caratterizzata dall'esordio, in età adulta, di chiazze di alopecia color carne, irregolari, prevalentemente nelle regioni parietali e del vertice del cuoio capelluto, in assenza di ipercheratosi follicolare o infiammazione perifollicolare."},"nl":{"name":"Pseudopelade van Brocq","definition":"Pseudopelade van Brocq is een zeldzame afwijking van haar, gekenmerkt door aanvang in de in volwassenheid van zachte, onregelmatige, vleeskleurige plekken van alopecie, vooral ter hoogte van de slapen en de kruin, zonder folliculaire hyperkeratose of perifolliculaire inflammatie."},"pt":{"name":"Pseudo-pelada de Brocq"},"pl":{"name":"Łysienie rzekomo bliznowaciejące Brocqa"},"cs":{"name":"Alopecia areata atrophicans","synonyms":["Pseudopelade Brocq"]},"uk":{"name":"Псевдопелада Брока","definition":"Pseudo-pelade of Brocq is a rare hair abnormality characterized by onset in adulthood of soft, irregular, flesh-toned patches of alopecia primarily in the parietal and vertex portions of the scalp, without follicular hyperkeratosis or perifollicular inflammation."},"zh":{"name":"Brocq假性斑秃"},"tr":{"name":"Brocq psödopelad"}},"xrefs":[{"source":"ICD-10","code":"L66.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"ED70.5Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1196440271"},{"source":"MONDO","code":"0015261","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0086873","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"4536","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":89826,"name":"Rare skin disease"},"parents":[{"orpha":79364,"name":"Alopecia","classifications":[187]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2026-02-24","source":"40109647[PMID]_37196297[PMID]_25114452[PMID]","terms":[{"hpo":"HP:0001595","label":"Abnormality of the hair","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001596","label":"Alopecia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0004529","label":"Atrophic, patchy alopecia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002287","label":"Progressive alopecia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001053","label":"Hypopigmented skin patches","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002960","label":"Autoimmunity","frequency":"Excluded (0%)","criteria":null},{"hpo":"HP:0025084","label":"Folliculitis","frequency":"Excluded (0%)","criteria":null}]}}