{"orpha":108,"name":"Babesiosis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Babesiosis is an infectious disease caused by protozoa of the genus <i>Babesia</i> and characterized by a febrile illness and hemolytic anemia but with manifestations ranging from an asymptomatic infection to a fulminating illness that can result in death.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-108/","orphanet_url":"https://www.orpha.net/en/disease/detail/108","names":{"fr":{"name":"Babésiose","definition":"La babésiose est une maladie infectieuse causée par un protozoaire du genre <i>Babesia</i>. Elle se caractérise par une maladie fébrile, une anémie hémolytique, et des manifestations variant d'une infection asymptomatique à une maladie fulminante pouvant être fatale."},"de":{"name":"Babesiose","definition":"Die Babesiose ist eine durch Protozoen der Gattung <i>Babesia</i> verursachte Infektionskrankheit. Sie ist gekennzeichnet durch Fieber und hämolytische Anämie, jedoch reicht das klinische Bild von symptomfreier Infektion bis zu schwerem Verlauf mit tödlichem Ausgang."},"es":{"name":"Babesiosis","definition":"La babesiosis es una enfermedad infecciosa causada por protozoos del género Babesia y caracterizada por un estado febril y anemia hemolítica, pero con manifestaciones que van desde la infección asintomática hasta una enfermedad fulminante que puede provocar la muerte."},"it":{"name":"Babesiosi","definition":"La babesiosi è una malattia infettiva da protozoi del genere <i>Babesia</i>, caratterizzata da malattia febbrile con anemia emolitica e segni che variano dall'infezione asintomatica alla malattia fulminante che esita nel decesso."},"nl":{"name":"Babesiose","definition":"Babesiose is een infectieziekte veroorzaakt door protozoa van het genus <i>Babesia</i> en die gekenmerkt wordt door een febriele ziekte en hemolytische anemie, maar met manifestaties gaande van een asymptomatische infectie tot een fulminante ziekte die kan resulteren in overlijden."},"pt":{"name":"Babesiose"},"pl":{"name":"Babeszioza","definition":"Babeszioza jest chorobą infekcyjną wywołaną przez pierwotniaki rodzaju Babezia, która charakteryzuje się gorączką i anemią hemolityczną, może przebiegać jako bezobjawowa infekcja, albo mieć piorunujący przebieg kończący się śmiercią."},"cs":{"name":"Babezióza"},"uk":{"name":"Бабезіоз","definition":"Babesiosis is an infectious disease caused by protozoa of the genus <i>Babesia</i> and characterized by a febrile illness and hemolytic anemia but with manifestations ranging from an asymptomatic infection to a fulminating illness that can result in death."},"zh":{"name":"巴贝虫病"},"tr":{"name":"Babeziyoz"}},"xrefs":[{"source":"ICD-10","code":"B60.0","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1F52","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1947003329"},{"source":"MONDO","code":"0005661","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D001404","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0004576","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"5878","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10003965","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"emedicine[OTHER]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0001945","label":"Fever","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002315","label":"Headache","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001878","label":"Hemolytic anemia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002829","label":"Arthralgia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012735","label":"Cough","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012378","label":"Fatigue","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002240","label":"Hepatomegaly","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000975","label":"Hyperhidrosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000952","label":"Jaundice","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001882","label":"Leukopenia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003326","label":"Myalgia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002719","label":"Recurrent infections","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001744","label":"Splenomegaly","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001873","label":"Thrombocytopenia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002039","label":"Anorexia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001864","label":"Clinodactyly of the 5th toe","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001259","label":"Coma","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001289","label":"Confusion","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001635","label":"Congestive heart failure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000716","label":"Depression","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0005521","label":"Disseminated intravascular coagulation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001399","label":"Hepatic failure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100724","label":"Hypercoagulability","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001376","label":"Limitation of joint mobility","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001658","label":"Myocardial infarction","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002017","label":"Nausea and vomiting","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000613","label":"Photophobia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100776","label":"Recurrent pharyngitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000083","label":"Renal insufficiency","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002093","label":"Respiratory insufficiency","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004936","label":"Venous thrombosis","frequency":"Occasional (29-5%)","criteria":null}]}}