{"orpha":1077,"name":"Dental ankylosis","type":"Malformation syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["Ankylosis of teeth"],"definition":"A rare odontologic disorder characterized by the loss of the periodontal ligament space and orthodontic mobility.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-1077/","orphanet_url":"https://www.orpha.net/en/disease/detail/1077","names":{"fr":{"name":"Ankylose dentaire","synonyms":["Ankylose des dents"],"definition":"Une anomalie dentaire caractérisée par la disparition du ligament parodontal et l'absence de mobilité."},"de":{"name":"Dentale Ankylose","synonyms":["Ankylose der Zähne"],"definition":"Eine seltene Zahnerkrankung, die durch den Verlust des parodontalen Ligamentraums und der kieferorthopädischen Beweglichkeit gekennzeichnet ist."},"es":{"name":"Anquilosis dental","synonyms":["Anquilosis de los dientes"],"definition":"Es un trastorno odontológico poco común que se caracteriza por la pérdida del espacio del ligamento periodontal y la movilidad dental."},"it":{"name":"Anchilosi dentale","synonyms":["Anchilosi dei denti"],"definition":"Si tratta di una malattia odontologica caratterizzata dalla perdita del legamento periodontale e del movimento ortodontico."},"nl":{"name":"Dentale ankylose","synonyms":["Ankylose van de tanden"],"definition":"Een zeldzame odontologische aandoening, gekarakteriseerd door verlies van periodontale spleet en tandmobiliteit."},"pt":{"name":"Anquilose dentária","synonyms":["Anquilose dos dentes"]},"pl":{"name":"Ankyloza zębów","synonyms":["Ankylosis of teeth"]},"cs":{"name":"Zubní ankylóza","synonyms":["Ankylóza zubů"]},"uk":{"name":"Зубний анкілоз","synonyms":["Анкілоз зубів"],"definition":"A rare odontologic disorder characterized by the loss of the periodontal ligament space and orthodontic mobility."},"zh":{"name":"牙-牙槽骨骨性黏连","synonyms":["牙-牙槽骨骨性黏连"]},"tr":{"name":"Dental ankiloz","synonyms":["Dişlerin ankilozu"]}},"xrefs":[{"source":"ICD-10","code":"K03.5","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"DA07.61","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"2066427602"},{"source":"MONDO","code":"0008007","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D020254","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0155930","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"701","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10044019","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98026,"name":"Rare odontologic disease"},"parents":[{"orpha":420755,"name":"Rare genetic odontal or periodontal disorder","classifications":[156]},{"orpha":164001,"name":"Rare odontal or periodontal disorder","classifications":[197]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adolescent","Adult","Childhood","Elderly"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0009804","label":"Tooth agenesis","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000682","label":"Abnormality of dental enamel","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0004209","label":"Clinodactyly of the 5th finger","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000303","label":"Mandibular prognathia","frequency":"Occasional (29-5%)","criteria":null}]}}