{"orpha":101992,"name":"Immunodeficiency due to a complement cascade protein anomaly","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-101992/","orphanet_url":"https://www.orpha.net/en/disease/detail/101992","names":{"fr":{"name":"Déficit immunitaire dû à une anomalie de la cascade du complément","synonyms":["Immunodéficience due à une anomalie de la cascade du complément"]},"de":{"name":"Immundefekt mit Störung des Komplement-Aktivierungsweg"},"es":{"name":"Inmunodeficiencia por anomalía en la cascada del complemento"},"it":{"name":"Immunodeficienza da anomalie delle proteine della cascata del complemento"},"nl":{"name":"Immuundeficiëntie door een complementcascade-eiwitanomalie"},"pt":{"name":"Imunodeficiência por anomalia da via alternativa do complemento"},"pl":{"name":"Niedobór odporności z powodu anomalii białek układu dopełniacza"},"cs":{"name":"Imunodeficience způsobená proteinovou anomálií v kaskádě komplementu"},"uk":{"name":"Імунодефіцит внаслідок аномалії білка каскаду комплементу"},"zh":{"name":"补体级联蛋白异常所致免疫缺陷"},"tr":{"name":"Kompleman kaskad protein anomalisine bağlı immün yetmezlik"}},"xrefs":[{"source":"ICD-10","code":"D84.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"4A00.1","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1222145690"},{"source":"MONDO","code":"15136","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681769","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19811","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":101988,"name":"Primary immunodeficiency due to a defect in innate immunity","classifications":[156,195]}],"children":[{"orpha":459345,"name":"Immunodeficiency due to a complement cascade component deficiency","type":"Category"},{"orpha":459348,"name":"Immunodeficiency due to a complement regulatory deficiency","type":"Category"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}