{"orpha":101978,"name":"OBSOLETE: Disease with severe reduction in all serum immunoglobulin isotypes with profoundly decreased or absent B cells","type":"Category","group":"Group of disorders","status":"inactive","flags":["Obsolete entity"],"synonyms":[],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.<br/><br/>Instead, consider using Immunodeficiency predominantly affecting antibody production","url":"https://raremap.alftech.space/d/ORPHA-101978/","orphanet_url":"https://www.orpha.net/en/disease/detail/101978","names":{"fr":{"name":"OBSOLETE : Maladie avec diminution importante d'immunoglobulines sériques et diminution ou absence de cellules B"},"de":{"name":"OBSOLET: Krankheit mit schwerer Reduktion der Serum-Immunglobuline aller Isotypen und deutlich reduzierten oder fehlenden B-Zellen"},"es":{"name":"OBSOLETO: Enfermedad con reducción grave de los isotipos de inmonoglobulinas séricas y con ausencia o disminución profunda de células B"},"it":{"name":"OBSOLETO: Agammaglobulinemia"},"nl":{"name":"OBSOLEET: Ziekte met ernstige vermindering van alle serumimmunoglobuline-isotypes met sterk verminderde of afwezige B-cellen"},"pt":{"name":"OBSOLETO: Doença com redução grave de todas os isotipos de imunoglobulinas séricas e com ausência ou diminuição acentuada de células B"},"pl":{"name":"NIEAKTUALNE: Choroba ze znacznym niedoborem wszystkich izotypów immunoglobulin osocza z glebokim obnizeniem lub brakiem komórek B"},"cs":{"name":"NEAKTUÁLNÍ: Onemocnění se závažným snížením všech izotypů sérových imunoglobulinů s hluboce sníženými nebo chybějícími B-buňkami"},"uk":{"name":"ЗАСТАРІЛО: Захворювання з вираженим зниженням усіх ізотипів імуноглобулінів у сироватці крові з глибоким зниженням або відсутністю В-лімфоцитів"},"zh":{"name":"弃用：所有血清同型免疫球蛋白严重减少和B细胞显著减少或缺失的疾病"},"tr":{"name":"Eski adı: B hücrelerinin tamamen azaldığı veya olmadığı tüm serum immünoglobulin izotiplerinde ağır azalma ile seyreden hastalık"}},"xrefs":[],"associations":[{"type":"Referred to","orpha":101977,"name":"Immunodeficiency due to predominantly antibodies defect"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}