{"orpha":101977,"name":"Immunodeficiency due to predominantly antibodies defect","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":["PAD","Predominantly antibodies deficiency"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-101977/","orphanet_url":"https://www.orpha.net/en/disease/detail/101977","names":{"fr":{"name":"Déficit immunitaire par déficit de production d'anticorps","synonyms":["PAD","Immunodéficience par déficit de production d'anticorps"]},"de":{"name":"Immundefekt durch vorwiegenden Antikörperdefekt","synonyms":["PAD","Vorwiegender Antikörpermangel","Immundefekt mit vorwiegender Beeinträchtigung der Antikörper-Produktion"]},"es":{"name":"Inmunodeficiencia con predominio de defectos de los anticuerpos","synonyms":["Deficiencia predominantemente de anticuerpos"]},"it":{"name":"Immunodeficienza da deficit prevalente degli anticorpi","synonyms":["PAD","Deficit prevalente degli anticorpi"]},"nl":{"name":"Immuundeficiëntie door voornamelijk defect van antilichamen","synonyms":["PAD","Voornamelijk deficiëntie van antilichamen"]},"pt":{"name":"Imunodeficiência afetando predominantemente a produção de anticorpos"},"pl":{"name":"Niedobór odporności dotyczący głównie produkcji przeciwciał","synonyms":["PAD","Predominantly antibodies deficiency"]},"cs":{"name":"Imunodeficience postihující převážně produkci protilátek","synonyms":["PAD","Predominantly antibodies deficiency"]},"uk":{"name":"Імунодефіцит, що переважно уражує вироблення антитіл"},"zh":{"name":"主要影响抗体产生的免疫缺陷"},"tr":{"name":"Ağırlıklı antikor üretimini etkileyen immün yetmezlik"}},"xrefs":[{"source":"ICD-11","code":"4A01.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"85074116"},{"source":"MONDO","code":"15132","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681776","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":2621,"name":"OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome","status":"inactive"},{"type":"Referred to","orpha":99972,"name":"OBSOLETE: Immunoglobulin A1 deficiency","status":"inactive"},{"type":"Referred to","orpha":99973,"name":"OBSOLETE: Immunoglobulin A2 deficiency","status":"inactive"},{"type":"Referred to","orpha":101978,"name":"OBSOLETE: Disease with severe reduction in all serum immunoglobulin isotypes with profoundly decreased or absent B cells","status":"inactive"},{"type":"Referred to","orpha":331244,"name":"OBSOLETE: Other immunodeficiency syndrome with predominantly antibody defects","status":"inactive"}],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":179006,"name":"Primary immunodeficiency due to a defect in adaptive immunity","classifications":[156,195]}],"children":[{"orpha":183669,"name":"Agammaglobulinemia","type":"Category"},{"orpha":1006,"name":"Alopecia antibody deficiency","type":"Disease"},{"orpha":696851,"name":"Common variable immunodeficiency and related disorders","type":"Category"},{"orpha":331232,"name":"Immunodeficiency with isotype or light chain deficiencies with normal number of B-cells","type":"Category"},{"orpha":331240,"name":"Immunodeficiency with severe reduction in serum IgG and IgA with normal/elevated IgM and normal number of B-cells","type":"Category"},{"orpha":178389,"name":"Osteopetrosis-hypogammaglobulinemia syndrome","type":"Disease"},{"orpha":3132,"name":"Say-Barber-Miller syndrome","type":"Malformation syndrome"},{"orpha":169443,"name":"Specific antibody deficiency with normal immunoglobulin concentrations and normal numbers of B cells","type":"Category"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}