{"orpha":101334,"name":"African tick typhus","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare bacterial infectious disease caused by the tick-borne bacterium <i>Rickettsia africae</i>, characterized by acute onset of fever accompanied by myalgia, localized lymphadenitis, and a papulovesicular rash. In most cases at least one, sometimes multiple, inoculation eschars are observed. Clustering of cases is frequent.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-101334/","orphanet_url":"https://www.orpha.net/en/disease/detail/101334","names":{"fr":{"name":"Typhus à tiques africain","definition":"Maladie infectieuse bactérienne rare causée par la bactérie <i>Rickettsia africae</i> transmise par les tiques et caractérisée par l'apparition aiguë d'une fièvre accompagnée de myalgies, d'une lymphadénite localisée et d'une éruption papulovésiculaire. Dans la plupart des cas, on observe au moins une, parfois plusieurs, escarres d'inoculation. Les cas groupés sont fréquents."},"de":{"name":"Afrikanisches Zeckenbissfieber","definition":"Eine seltene bakterielle Infektionskrankheit, die durch das von Zecken übertragene Bakterium <i>Rickettsia africae</i> verursacht wird und durch akut einsetzendes Fieber, begleitet von Myalgie, lokalisierter Lymphadenitis und einem papulovesikulären Ausschlag gekennzeichnet ist. In den meisten Fällen werden mindestens eine, manchmal auch mehrere Inokulationsnarben beobachtet. Eine Häufung von Fällen ist häufig."},"es":{"name":"Tifus africano transmitido por garrapatas","definition":"Es una enfermedad infecciosa bacteriana poco frecuente causada por la bacteria <i>Rickettsia africae</i> transmitida por garrapatas, caracterizada por un inicio agudo de fiebre acompañada de mialgia, linfadenitis localizada y una erupción papulovesicular. En la mayoría de los casos, se observa al menos una, en ocasiones múltiples, escaras de inoculación. La agrupación de los casos es frecuente."},"it":{"name":"Tifo africano da zecche","definition":"Si tratta di una malattia infettiva batterica rara, causata dal batterio trasmesso dalle zecche <i>Rickettsia africae</i>, caratterizzata da febbre ad esordio acuto associata a mialgia, linfoadenite localizzata ed eruzione papulo-vescicolare. Nella maggior parte dei casi, si osserva almeno un'escara (talvolta più di una) nel punto d'inoculazione. Spesso si osserva una concentrazione di casi."},"nl":{"name":"Afrikaanse teektyfus","definition":"Een zeldzame, bacteriële infectieziekte, veroorzaakt door de door teken overgedragen bacterie <i>Rickettsia africae</i>, en gekarakteriseerd door acute aanvang van koorts vergezeld van myalgie, gelokaliseerde lymfadenitis, en papulovesiculaire huiduitslag. In de meeste gevallen wordt minstens één, soms meerdere, eschars waargenomen op de plaats van inoculatie. Clustering van gevallen komt vaak voor."},"pt":{"name":"African tick typhus"},"pl":{"name":"Dur kleszczowy afrykański"},"cs":{"name":"Africká klíšťová horečka"},"uk":{"name":"Африканський кліщовий висипний тиф","definition":"A rare bacterial infectious disease caused by the tick-borne bacterium <i>Rickettsia africae</i>, characterized by acute onset of fever accompanied by myalgia, localized lymphadenitis, and a papulovesicular rash. In most cases at least one, sometimes multiple, inoculation eschars are observed. Clustering of cases is frequent."},"zh":{"name":"非洲蜱传斑疹伤寒","definition":"非洲蜱斑疹伤寒是一种罕见的细菌性传染病，由蜱传细菌非洲立克次体引起，特征是急性发热伴有肌肉痛、局限性淋巴结炎和丘疹。在大多数情况下，观察到至少一种接种焦痂，有时是多次接种焦痂。病例聚集性较高。"},"tr":{"name":"Afrika kene tifüsü"}},"xrefs":[{"source":"ICD-10","code":"A77.1","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"1C31.1","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1771381430"},{"source":"UMLS","code":"C1320317","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19781","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":102022,"name":"Spotted fever rickettsiosis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}