{"orpha":100979,"name":"Autosomal dominant complex spastic paraplegia","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Autosomal dominant complex HSP","Autosomal dominant complex SPG","Autosomal dominant complicated HSP","Autosomal dominant complicated SPG","Autosomal dominant complicated spastic paraplegia"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-100979/","orphanet_url":"https://www.orpha.net/en/disease/detail/100979","names":{"fr":{"name":"Paraplégie spastique complexe autosomique dominante","synonyms":["HSP complexe autosomique dominante","SPG complexe autosomique dominante"]},"de":{"name":"Hereditäre spastische Paraplegie, autosomal-dominante komplexe"},"es":{"name":"Paraplejía espástica hereditaria autosómica dominante compleja"},"it":{"name":"Paraplegia spastica ereditaria, autosomica dominante complessa"},"nl":{"name":"Autosomaal dominante complexe spastische paraplegie"},"pt":{"name":"Paraplegia espástica complexa autossómica dominante"},"pl":{"name":"Autosomalna dominująca złożona paraplegia spastyczna","synonyms":["Autosomalna dominująca powikłana HSP","Autosomalna dominująca powikłana paraplegia spastyczna","Autosomalna dominująca powikłana SPG","Autosomalna dominująca złożona HSP","Autosomalna dominująca złożona SPG"]},"cs":{"name":"Autozomálně dominantní komplexní spastická paraplegie","synonyms":["Autozomálně dominantní komplexní HSP","Autozomálně dominantní komplexní SPG","Autozomálně dominantní komplikovaná HSP","Autozomálně dominantní komplikovaná SPG","Autozomálně dominantní komplikovaná spastická paraplegie"]},"uk":{"name":"Аутосомно-домінантна складна спастична параплегія","synonyms":["Аутосомно-домінантний комплекс HSP","Аутосомно-домінантний комплекс SPG","Аутосомно-домінантний ускладнений HSP","Аутосомно-домінантна ускладнена спастична параплегія","Аутосомно-домінантний ускладнений SPG"]},"zh":{"name":"常染色体显性遗传遗传复杂痉挛性截瘫","synonyms":["常染色体显性遗传复杂型SPG"]},"tr":{"name":"Otozomal dominant kompleks spastik parapleji","synonyms":["Otozomal baskın kompleks HSP","Otozomal baskın kompleks KMT","Otozomal baskın komplike HSP","Otozomal baskın komplike SPG","Otozomal baskın komplike spastik parapleji"]}},"xrefs":[{"source":"MONDO","code":"0015087","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"15087","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680379","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"19770","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":100990,"name":"OBSOLETE: Autosomal dominant spastic paraplegia type 9","status":"inactive"}],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":102013,"name":"Complex hereditary spastic paraplegia","classifications":[156,181]}],"children":[{"orpha":100998,"name":"Autosomal dominant spastic paraplegia type 17","type":"Disease"},{"orpha":101009,"name":"Autosomal dominant spastic paraplegia type 29","type":"Disease"},{"orpha":320365,"name":"Autosomal dominant spastic paraplegia type 36","type":"Disease"},{"orpha":171617,"name":"Autosomal dominant spastic paraplegia type 38","type":"Disease"},{"orpha":447753,"name":"Autosomal dominant spastic paraplegia type 9A","type":"Disease"},{"orpha":615938,"name":"Spastic paraparesis-cataracts-speech delay syndrome","type":"Clinical syndrome"},{"orpha":329475,"name":"Spastic paraplegia-Paget disease of bone syndrome","type":"Disease"},{"orpha":2819,"name":"Spastic paraplegia-facial-cutaneous lesions syndrome","type":"Malformation syndrome"},{"orpha":521390,"name":"Spastic paraplegia-intellectual disability-nystagmus-obesity syndrome","type":"Malformation syndrome"},{"orpha":2820,"name":"Spastic paraplegia-nephritis-deafness syndrome","type":"Clinical syndrome"},{"orpha":2821,"name":"Spastic paraplegia-neuropathy-poikiloderma syndrome","type":"Disease"},{"orpha":2826,"name":"Spastic paraplegia-precocious puberty syndrome","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Autosomal dominant"],"onset":[],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":1.0,"area":"Norway","status":"Validated","source":"19339254[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"1-9 / 100 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}