Caribbean parkinsonism
Synonyms: Atypical parkinsonism in the Caribbean
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adult, Elderly
- Status
- active
Parkinsonism with dementia of Guadeloupe is characterised by symmetrical bradykinesia, predominantly axial rigidity, postural instability with early falls and cognitive decline with prominent features of frontal lobe dysfunction.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Caribbean parkinsonism | Atypical parkinsonism in the Caribbean |
| fr | Parkinsonisme des Caraïbes | Parkinsonisme atypique des Caraïbes |
| de | Karibisches Parkinson-Syndrom | Atypisches Parkinson-Syndrom der Karibik |
| es | Parkinsonismo caribeño | Parkinsonismo atípico en el Caribe |
| it | Parkinsonismo con demenza della Guadalupa | |
| nl | Caribisch parkinsonisme | Atypisch parkinsonisme in de Caraïben |
| pt | Parkinsonismo com demência de Guadeloupe | |
| pl | Odmiana karaibska choroby Parkinsona | = en |
| cs | Guadeloupský parkinsonský komplex | = en |
| uk | Карибський паркінсонізм | Атиповий паркінсонізм у Карибському басейні |
| zh | 加勒比海帕金森病 | 加勒比海非典型帕金森病 |
| tr | Karayip parkinsonizmi | Karayipler'de atipik parkinsonizm |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | F02.3* | NTBT | attributed | validated |
| ICD-10 | G20+ | NTBT | attributed | validated |
| ICD-11 | 8A00.1Y | NTBT | attributed | validated |
| MONDO | 0019977 | E | validated | |
| UMLS | C4275027 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:89043Rare dementia
rare neurological diseases - ORPHA:306666Rare parkinsonian syndrome due to neurodegenerative disease
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
27 annotations · validated 2018-06-11| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002067 | Bradykinesia | |
| HP:0001300 | Parkinsonism | |
| HP:0002063 | Rigidity | |
| Frequent (79-30%) | ||
| HP:0012332 | Abnormal autonomic nervous system physiology | |
| HP:0002345 | Action tremor | |
| HP:0002186 | Apraxia | |
| HP:0005341 | Autonomic bladder dysfunction | |
| HP:0002120 | Cerebral cortical atrophy | |
| HP:0000726 | Dementia | |
| HP:0001332 | Dystonia | |
| HP:0003458 | EMG: myopathic abnormalities | |
| HP:0000727 | Frontal lobe dementia | |
| HP:0000738 | Hallucinations | |
| HP:0000571 | Hypometric saccades | |
| HP:0007045 | Midline brain calcifications | |
| HP:0001336 | Myoclonus | |
| HP:0001278 | Orthostatic hypotension | |
| HP:0030902 | Palmomental reflex | |
| HP:0002172 | Postural instability | |
| HP:0007240 | Progressive gait ataxia | |
| HP:0002193 | Pseudobulbar behavioral symptoms | |
| HP:0002360 | Sleep abnormality | |
| HP:0012753 | T2 hypointense basal ganglia | |
| HP:0002119 | Ventriculomegaly | |
| HP:0000511 | Vertical supranuclear gaze palsy | |
| HP:0010549 | Weakness due to upper motor neuron dysfunction | |
| Excluded (0%) | ||
| HP:0100315 | Lewy bodies | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 29525296[PMID]_18941145[PMID]_18816693[PMID]_17303592[PMID]_1210440304[PMID]_217621[PMID]_11912113[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/97355
- This record as JSON: /data/d/97355.json