Thyroid lymphoma
- Type
- Disease
- Group
- Disorder
- Age of onset
- No data available
- Status
- active
A rare primary organ-specific lymphoma characterized by primary origin in the thyroid gland, sometimes involving cervical lymph nodes, and infrequently more distant sites. Diffuse large B-cell lymphoma is most common, followed by MALT lymphoma, and follicular lymphoma. More rare types include T-cell lymphomas, Burkitt lymphoma, or classic Hodgkin lymphoma. The condition is usually associated with Hashimoto thyroiditis. Patients typically present with a mass in the thyroid, with or without cervical lymphadenopathy. Hoarseness and dyspnea may occur, while constitutional symptoms are rare. Prognosis is favorable for patients with localized tumors.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Thyroid lymphoma | |
| fr | Lymphome thyroïdien | |
| de | Schilddrüsenlymphom | |
| es | Linfoma tiroideo | |
| it | Linfoma tiroideo | |
| nl | Schildklierlymfoom | |
| pt | Linfoma da tiroide | |
| pl | Chłoniak tarczycy | |
| cs | Lymfom štítné žlázy | |
| uk | Лімфома щитовидної залози | |
| zh | 甲状腺淋巴瘤 | |
| tr | Tiroid lenfoması |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C85.7 | NTBT | attributed | validated |
| ICD-11 | 2B33.5 | NTBT | index | validated |
| MONDO | 0019962 | E | validated | |
| UMLS | C1336753 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:279911Primary organ-specific lymphoma
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders - ORPHA:100087Rare thyroid tumor
rare endocrine diseases; rare neoplastic diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | Unknown | — | Worldwide | Class only | Not yet validated | 23714679[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
14 annotations · validated 2016-06-08| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Obligate (100%) | ||
| HP:0000853 | Goiter | |
| HP:0002665 | Lymphoma | |
| Very frequent (99-80%) | ||
| HP:0000475 | Broad neck | |
| Frequent (79-30%) | ||
| HP:0002015 | Dysphagia | |
| HP:0002094 | Dyspnea | |
| HP:0000872 | Hashimoto thyroiditis | |
| HP:0001609 | Hoarse voice | |
| HP:0000821 | Hypothyroidism | |
| HP:0002716 | Lymphadenopathy | |
| HP:0010307 | Stridor | |
| HP:0002781 | Upper airway obstruction | |
| Occasional (29-5%) | ||
| HP:0000836 | Hyperthyroidism | |
| HP:0012531 | Pain | |
| Very rare (<4-1%) | ||
| HP:0002098 | Respiratory distress | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 23714679[PMID]_24077086[PMID]_20497878[PMID]_12417514[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/97285
- This record as JSON: /data/d/97285.json