Mills syndrome
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adolescent, Adult, Childhood, Elderly
- Status
- active
A rare, acquired motor neuron disease characterized by a slowly progressive, unilateral, ascending or descending hemiplegia, associated to unilateral or asymmetrical pyramidal signs and no sensory loss. It is a diagnosis of exclusion and controversy exists regarding whether the presence of bulbar symptoms, sphincter disturbances, fasciculations or cognitive manifestations characterize the disease.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Mills syndrome | |
| fr | Syndrome de Mills | |
| de | Mills-Syndrom | |
| es | Síndrome de Mills | |
| it | Sindrome di Mills | Sclerosi laterale amiotrofica, tipo emiplegico |
| nl | Syndroom van Mills | |
| pt | Síndrome de Mills | |
| pl | Zespół Millsa | Stwardnienie zanikowe boczne, typu porażenie połowicze |
| cs | Millsův syndrom | Amyotrofická laterální skleróza, hemiplegický typ |
| uk | Синдром Міллса | |
| zh | Mills综合征 | |
| tr | Mills sendromu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G12.2 | NTBT | attributed | validated |
| ICD-11 | 8B60.Y | NTBT | attributed | validated |
| MONDO | 0035892 | E | validated | |
| UMLS | C5191669 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98506Acquired motor neuron disease
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 1 000 000 | 0.12 / 100 000 | United Kingdom | Value and class | Validated | 30631918[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/94091
- This record as JSON: /data/d/94091.json