Moderate and severe traumatic brain injury
- Type
- Particular clinical situation in a disease or syndrome
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare neurologic condition characterized by brain damage caused by an external mechanical force, with a Glasgow Coma Scale score of 9 to 12 in moderate traumatic brain injury (TBI), or 3 to 8 in severe TBI, respectively. TBI can be closed (with the dura mater remaining intact) or open (with penetration of the dura mater) and may lead to focal damage, such as cerebral contusion and hemorrhage, as well as diffuse axonal injury and secondary damage due to increased intracranial pressure. Signs and symptoms are highly variable, depending on the nature, severity, localization, and extent of the trauma.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Moderate and severe traumatic brain injury | |
| fr | Lésion traumatique modérée ou sévère du cerveau | |
| de | Mittelschweres und schweres Schädel-Hirntrauma | |
| es | Daño cerebral traumático de moderado a grave | |
| it | Lesioni cerebrali traumatiche moderate e gravi | |
| nl | Matig en ernstig traumatisch hersenletsel | |
| pt | Lesão cerebral traumática moderada a grave | |
| pl | Umiarkowany lub ciężki uraz mózgu | |
| cs | Středně těžké a těžké traumatické poranění mozku | |
| uk | Черепно-мозкова травма середнього та тяжкого ступеня тяжкості | |
| zh | 中重度外伤性脑损伤 | |
| tr | Orta ve ağır travmatik beyin hasarı |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | S06.1 | NTBT | attributed | validated |
| ICD-10 | S06.2 | NTBT | attributed | validated |
| ICD-10 | S06.3 | NTBT | attributed | validated |
| ICD-10 | S06.4 | NTBT | attributed | validated |
| ICD-10 | S06.5 | NTBT | attributed | validated |
| ICD-10 | S06.6 | NTBT | attributed | validated |
| ICD-10 | S06.7 | NTBT | attributed | validated |
| ICD-10 | S06.8 | NTBT | attributed | validated |
| ICD-10 | S06.9 | NTBT | attributed | validated |
| UMLS | C5681362 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98006Rare neurologic disease
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 37.8 / 100 000 | Europe | Value and class | Validated | European Medicines Agency[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/90056
- This record as JSON: /data/d/90056.json