raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:90052

Recurrent hepatitis C virus induced liver disease in liver transplant recipients

Type
Particular clinical situation in a disease or syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare hepatic disease characterized by recurrence of hepatitis C virus infection after liver transplantation, leading to liver injury with features resembling those observed in the non-transplant graft, and typically developing after three months post-transplantation. The clinical course is highly variable, although patients most commonly develop progressive chronic liver disease with higher viral loads and more rapid fibrosis progression than in the immunocompetent population.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enRecurrent hepatitis C virus induced liver disease in liver transplant recipients
frManifestations hépatiques récurrentes causées par le virus de l'hépatite C chez les transplantés hépatiques
deRekurrente Hepatitis-C-Virus-induzierte Lebererkrankung bei Lebertransplantierten
esEnfermedad hepática por recurrencia del virus de la hepatitis C en trasplantados hepáticos
itEpatiti ricorrenti da virus dell'epatite C nei pazienti trapiantati di fegato
nlTerugkerende hepatitis C-virus-geïnduceerde leverziekte bij levertransplantaatrecipiënten
ptDoença hepática recorrente induzida pelo vírus da Hepatite C em recetores de transplante hepático
plNawracające zapalenie wątroby typu C indukujące chorobę wątroby u biorców przeszczepionej wątroby
csRekurentní postižení jater indukované virem hepatitidy C u příjemců transplantátu
ukРецидивуючі захворювання печінки, спричинені вірусом гепатиту С, у реципієнтів трансплантації печінки
zh复发性丙型肝炎病毒所致肝移植受者肝病
trKaraciğer nakli alıcılarında tekrarlayan hepatit C virüsünün neden olduğu karaciğer hastalığı

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10B18.2NTBTattributedvalidated
ICD-111E51.1NTBTattributedvalidated
UMLSC5681349Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (2):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalence1-9 / 100 0007 / 100 000EuropeValue and classValidatedEuropean Medicines Agency[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card