Florid cemento-osseous dysplasia
Synonyms: Florid osseous dysplasia · Focal cemento-osseous dysplasia
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
Florid cemento-osseous dysplasia (FCOD) is a rare fibro-osseous lesion in the jaw that predominantly affects middle-aged women of African descent. It is generally asymptomatic or may manifest with pain and gingival swelling. Radiologically, it is characterized by multiple dense lobulated bone lesions, often symmetrically located in various regions of the jaw.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Florid cemento-osseous dysplasia | Florid osseous dysplasia · Focal cemento-osseous dysplasia |
| fr | Dysplasie cémento-osseuse floride | Dysplasie cémento-osseuse focale · Dysplasie osseuse floride |
| de | Floride Knochenzement-Dysplasie | Dysplasie, floride ossäre |
| es | Displasia cemento-ósea florida | Displasia cemento-ósea focal · Displasia florida ósea · Displasia ósea florida |
| it | Displasia florida cemento-ossea | Displasia florida ossea · Displasia focale cemento-ossea |
| nl | Floride cemento-osseuze dysplasie | Floride osseuze dysplasie · Focale cemento-osseuze dysplasie |
| pt | Displasia cemento-óssea florida | Displasia cemento-óssea focal · Displasia óssea florida |
| pl | Rozsiana dysplazja cementowo-kostna | Ogniskowa dysplazja cementowo-kostna |
| cs | Floridní cementokostní dysplázie | Floridní kostní dysplázie · Fokální cementokostní dysplázie |
| uk | Флористична цементно-кісткова дисплазія | Флорідна кісткова дисплазія · Фокальна цементно-кісткова дисплазія |
| zh | 菜花样牙骨质-骨化不全 | 局灶性牙骨质-骨结构不良 |
| tr | Florid semento-osseoz displazisi | Florid kemik displazisi · Fokal semento-kemik displazisi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D16.4 | NTBT | index | validated |
| ICD-10 | D16.5 | NTBT | index | validated |
| ICD-11 | DA07.3 | NTBT | index | validated |
| MONDO | 0019368 | E | validated | |
| MeSH | C537063 | E | validated | |
| UMLS | C0555197 | E | validated | |
| GARD | 10173 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:164001Rare odontal or periodontal disorder
rare odontological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
23 annotations · validated 2021-10-05| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0003330 | Abnormal bone structure | |
| HP:0100671 | Abnormal trabecular bone morphology | |
| HP:0100717 | Abnormality of the cementum | |
| HP:0000277 | Abnormality of the mandible | |
| HP:0000326 | Abnormality of the maxilla | |
| Frequent (79-30%) | ||
| HP:0000309 | Abnormal midface morphology | |
| HP:0430028 | Hyperplasia of the maxilla | |
| HP:0001571 | Multiple impacted teeth | |
| HP:0000700 | Periapical bone loss | |
| Occasional (29-5%) | ||
| HP:0006483 | Abnormal number of teeth | |
| HP:0006481 | Abnormality of primary teeth | |
| HP:0006308 | Atrophy of alveolar ridges | |
| HP:0010885 | Avascular necrosis | |
| HP:0031035 | Chronic infection | |
| HP:0000689 | Dental malocclusion | |
| HP:0011968 | Feeding difficulties | |
| HP:0030793 | Jaw swelling | |
| HP:0007626 | Mandibular osteomyelitis | |
| HP:0012065 | Multiple bony cystic lesions | |
| HP:0000155 | Oral ulcer | |
| HP:0012531 | Pain | |
| HP:0009088 | Speech articulation difficulties | |
| HP:0011069 | Supernumerary tooth | |
Run the differential on the 5 obligate / very frequent terms
Annotation source: 31942128[PMID]_28194495[PMID]_32315206[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/83451
- This record as JSON: /data/d/83451.json