ORPHA:73267
Non-24-hour sleep-wake syndrome
Synonyms: Hypernychthemeral syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Unknown
- Age of onset
- All ages
- Status
- active
A rare neurological disease which is a circadian rhythm sleep disorder characterized by non-synchronization to a 24-hour day leading to insomnia and daytime sleepiness with sometimes severe associated manifestations.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Non-24-hour sleep-wake syndrome | Hypernychthemeral syndrome |
| fr | Syndrome du rythme différent de 24h | Rythme hypernyctéméral · Syndrome hypernyctéméral |
| de | Nicht-24-Stunden-Schlaf-Wach-Syndrom | Hypernykthemerales Syndrom |
| es | Síndrome de vigilia-sueño no de 24 horas | Síndrome hipernictemeral |
| it | Sindrome del ritmo sonno-veglia diverso dalle 24 ore | Sindrome della veglia di 24 ore · Sindrome ipernictemerale |
| nl | Niet-24-uurs slaap-waaksyndroom | Hypernychthemeraal syndroom |
| pt | Síndrome hipernictemeral | Síndrome ciclo sono-vigília não-24h |
| pl | Zespół nie-24-godzinnego rytmu snu-czuwania | Zespół wydłużonej doby |
| cs | Syndrom nesynchronizovaného 24-hodinového rytmu | Hypernychthemerální syndrom |
| uk | Синдром порушення 24-годинного циклу сну-неспання | Гіпернітеральний синдром |
| zh | 非24小时睡眠-觉醒综合征 | 超24小时综合征 |
| tr | 24 saatlik olmayan uyku-uyanıklık sendromu | Hipernikemeral sendromu |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G47.2 | NTBT | attributed | validated |
| ICD-11 | 7A6Z | NTBT | index | validated |
| MONDO | 0019137 | E | validated | |
| UMLS | C5545668 | E | validated | |
| GARD | 10949 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:68354Rare sleep disorder
rare neurological diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
5 annotations · validated 2018-09-17| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0012689 | Abnormal pineal melatonin secretion | |
| HP:0025406 | Asthenia | |
| HP:0000618 | Blindness | |
| HP:0000716 | Depression | |
| HP:0001262 | Excessive daytime somnolence | |
Annotation source: 1435929[PMID]_18041479[PMID]_23385698[PMID]_26568125[PMID]_27500861[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/73267
- This record as JSON: /data/d/73267.json