Zygomycosis
Synonyms: Mucormycosis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare mycosis caused by ubiquitous, opportunistic fungi of the order Mucorales, characterized by tissue infarction and necrosis due to invasion of the vasculature by hyphae. The spectrum of clinical manifestations depends on the route of infection and includes rhinocerebral, pulmonary, cutaneous, gastrointestinal, renal, and disseminated forms. The disease is usually rapidly progressive and associated with high mortality.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Zygomycosis | Mucormycosis |
| fr | Zygomycose | Mucormycose |
| de | Zygomykose | Mukormykose |
| es | Zigomicosis | Mucormicosis |
| it | Zigomicosi | Mucormicosi |
| nl | Zygomycose | Mucormycose |
| pt | Zigomicose | Mucormicose |
| pl | Mukormykoza | Mukormikoza |
| cs | Zygomykóza | Mukormykóza |
| uk | Зигомікоз | Мукормікоз |
| zh | 接合菌病 | 毛霉菌病 |
| tr | Zigomikoz | Mukormikoz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B46.0 | BTNT | specific | validated |
| ICD-10 | B46.1 | BTNT | specific | validated |
| ICD-10 | B46.2 | BTNT | specific | validated |
| ICD-10 | B46.3 | BTNT | specific | validated |
| ICD-10 | B46.4 | BTNT | specific | validated |
| ICD-10 | B46.5 | BTNT | specific | validated |
| ICD-10 | B46.8 | BTNT | specific | validated |
| ICD-10 | B46.9 | BTNT | specific | validated |
| ICD-11 | 1F2C | E | specific | validated |
| MONDO | 0019136 | E | validated | |
| MeSH | D020096 | E | validated | |
| UMLS | C0043541 | E | validated | |
| GARD | 10224 | E | validated | |
| MedDRA | 10061418 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163591Rare mycosis
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
76 annotations · validated 2020-04-21| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0012735 | Cough | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0012531 | Pain | |
| HP:0000246 | Sinusitis | |
| HP:0032162 | Unusual skin infection | |
| Occasional (29-5%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0008066 | Abnormal blistering of the skin | |
| HP:0001291 | Abnormal cranial nerve morphology | |
| HP:0045026 | Abnormal mediastinum morphology | |
| HP:0011949 | Acute infectious pneumonia | |
| HP:0032172 | Air crescent sign | |
| HP:0100750 | Atelectasis | |
| HP:0000622 | Blurred vision | |
| HP:0100658 | Cellulitis | |
| HP:0100749 | Chest pain | |
| HP:0002583 | Colitis | |
| HP:0032674 | Cutaneous wound | |
| HP:0001875 | Decreased total neutrophil count | |
| HP:0000819 | Diabetes mellitus | |
| HP:0002014 | Diarrhea | |
| HP:0004387 | Enterocolitis | |
| HP:0100537 | Fasciitis | |
| HP:0005263 | Gastritis | |
| HP:0002315 | Headache | |
| HP:0002248 | Hematemesis | |
| HP:0004377 | Hematological neoplasm | |
| HP:0002105 | Hemoptysis | |
| HP:0032564 | Ileitis | |
| HP:0002383 | Infectious encephalitis | |
| HP:0001993 | Ketoacidosis | |
| HP:0100721 | Mediastinal lymphadenopathy | |
| HP:0001742 | Nasal congestion | |
| HP:0002018 | Nausea | |
| HP:0032177 | Parenchymal consolidation | |
| HP:0100539 | Periorbital edema | |
| HP:0000629 | Periorbital fullness | |
| HP:0002202 | Pleural effusion | |
| HP:0002107 | Pneumothorax | |
| HP:0001622 | Premature birth | |
| HP:0002113 | Pulmonary infiltrates | |
| HP:0200039 | Pustule | |
| HP:0031417 | Rhinorrhea | |
| HP:0200035 | Skin plaque | |
| HP:0032166 | Unusual gastrointestinal infection | |
| HP:0000572 | Visual loss | |
| HP:0002013 | Vomiting | |
| Very rare (<4-1%) | ||
| HP:0004420 | Arterial thrombosis | |
| HP:0030049 | Brain abscess | |
| HP:0012375 | Chemosis | |
| HP:0031369 | Colon perforation | |
| HP:0004944 | Dilatation of the cerebral artery | |
| HP:0000651 | Diplopia | |
| HP:0100584 | Endocarditis | |
| HP:0000421 | Epistaxis | |
| HP:0000544 | External ophthalmoplegia | |
| HP:0002239 | Gastrointestinal hemorrhage | |
| HP:0002573 | Hematochezia | |
| HP:0012115 | Hepatitis | |
| HP:0020101 | Invasive fungal infection | |
| HP:0007185 | Loss of consciousness | |
| HP:0000265 | Mastoiditis | |
| HP:0002249 | Melena | |
| HP:0012819 | Myocarditis | |
| HP:0000123 | Nephritis | |
| HP:0002797 | Osteolysis | |
| HP:0001733 | Pancreatitis | |
| HP:0001701 | Pericarditis | |
| HP:0002586 | Peritonitis | |
| HP:0000520 | Proptosis | |
| HP:0000508 | Ptosis | |
| HP:0000083 | Renal insufficiency | |
| HP:0025326 | Retinal arterial occlusion | |
| HP:0000541 | Retinal detachment | |
| HP:0025059 | Splenic abscess | |
| HP:0004418 | Thrombophlebitis | |
Annotation source: 17848885[PMID]_19754758[PMID]_16568297[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/73263
- This record as JSON: /data/d/73263.json