ORPHA:63275
Pemphigoid gestationis
Synonyms: Gestational pemphigoid
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adolescent, Adult
- Status
- active
A rare autoimmune bullous skin disease characterized by pruritus with or without polymorphic skin eruption, affecting pregnant women typically during the second and third trimester.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Pemphigoid gestationis | Gestational pemphigoid |
| fr | Pemphigoïde gravidique | Pemphigoïde de la grossesse · Pemphigoïde gestationnelle |
| de | Pemphigoid gestationis | Schwangerschafts-Pemphigoid |
| es | Penfigoide gestationis | Herpes gestationis · Penfigoide gestacional |
| it | Pemfigoide gestazionale | Pemfigoide gravidico |
| nl | Pemphigoid gestationis | Gestationeel pemfigoïd |
| pt | Penfigoide gestacional | |
| pl | Pemfigoid ciężarnych | = en |
| cs | Gestační pemphigoid | Gestační pemfigoid |
| uk | Гестаційний пемфігоїд | Гестаційний пемфігоїд |
| zh | 妊娠性类天疱疮 | 妊娠性类天疱疮 |
| tr | Pemfigoid gestationis | Pemfigoid gestasyones |
Definition in:
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Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | O26.4 | NTBT | attributed | validated |
| ICD-11 | JA65.10 | E | specific | validated |
| MONDO | 0006558 | E | validated | |
| MeSH | D006559 | E | validated | |
| UMLS | C0019343 | E | validated | |
| GARD | 6497 | E | validated | |
| MedDRA | 10019939 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:79669Autoimmune bullous skin disease
rare skin diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
4 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.2 / 100 000 | Germany | Value and class | Validated | 19170813[PMID] |
| Annual incidence | <1 / 1 000 000 | 0.05 / 100 000 | France | Value and class | Validated | 7826096[PMID]_23237497[PMID] |
| Annual incidence | 1-9 / 1 000 000 | 0.18 / 100 000 | Kuwait | Value and class | Validated | 15569006[PMID] |
| Point prevalence | 1-9 / 1 000 000 | 0.693 / 100 000 | Germany | Value and class | Validated | 27456755[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
6 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0008066 | Abnormal blistering of the skin | |
| HP:0001622 | Premature birth | |
| HP:0000989 | Pruritus | |
| HP:0200037 | Skin vesicle | |
| Frequent (79-30%) | ||
| HP:0001508 | Failure to thrive | |
| HP:0001511 | Intrauterine growth retardation | |
Run the differential on the 4 obligate / very frequent terms
Annotation source: 25178359[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/63275
- This record as JSON: /data/d/63275.json