ORPHA:585909

B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)

Synonyms: B-ALL with t(9;22)(q34.1;q11.2) · BCR-ABL1-like B-ALL · Philadelphia chromosome-like B-ALL

Orphadata ships no English definition for this code.

Names in Orphadata languages

12 of 12 languages

Lang	Name	Synonyms
en	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	B-ALL with t(9;22)(q34.1;q11.2) · BCR-ABL1-like B-ALL · Philadelphia chromosome-like B-ALL
fr	Leucémie/lymphome lymphoblastique B associé à t(9;22)(q34.1;q11.2)	Leucémie/lymphome lymphoblastique B avec t(9;22)(q34.1;q11.2)
de	B-lymphoblastische Leukämie/Lymphom mit t(9;22)(q34.1;q11.2)	Philadelphia-Chromosom-ähnliche B-ALL · B-ALL mit t(9;22)(q34.1;q11.2) · BCR-ABL1-ähnliche B-ALL
es	Leucemia/linfoma linfoblástico de células B con t(9;22)(q34.1;q11.2)	LLA-B con t(9;22)(q34.1;q11.2) · LLA-B similar a BCR-ABL1 · LLA-B similar al cromosoma Filadelfia
it	'Leucemia linfoblastica a cellule B/linfoma con t(9;22)(q34.1;q11.2)'	LLA-B BCR-ABL1 simile · LLA-B con t(9;22)(q34.1;q11.2) · LLA-B cromosoma Philadelphia simile
nl	B-lymfoblastische leukemie/lymfoom met t(9;22)(q34.1;q11.2)	B-ALL met t(9;22)(q34.1;q11.2) · BCR-ABL1-achtige B-ALL · Philadelphia-chromosoomachtige B-ALL
pt	Leucemia/linfoma linfoblástico-B com t(9;22)(q34.1;q11.2)
pl	Białaczka limfoblastyczna/chłoniak z komórek B z t(9;22)(q34.1;q11.2)	= en
cs	B-lymfoblastická leukémie/lymfom s t(9;22)(q34.1;q11.2)	= en
uk	В-лімфобластний лейкоз/лімфома з t(9;22)(q34.1;q11.2)	B-ALL з t(9;22)(q34.1;q11.2) · BCR-ABL1-подібний B-ALL · Філадельфійська хромосома B-ALL
zh	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	= en
tr	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	= en

qualifier = Orphanet mapping relation

Source	Code	Qualifier	ICD relation	Validation
ICD-10	C91.0	NTBT	attributed	validated
ICD-11	2A70.1	E	specific	validated
MONDO	0035940	E		validated
UMLS	C5680319	E		validated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

ORPHA:99860Precursor B-cell acute lymphoblastic leukemia
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders

No children.

7 direct

Gene	Association	Status	HGNC	Ensembl	OMIM	Locus	Name	Source of validation
CDKN2A	Biomarker tested in	Assessed	HGNC:1787	ENSG00000147889	600160	9p21.3	cyclin dependent kinase inhibitor 2A	18838613[PMID]
IKZF1	Biomarker tested in	Assessed	HGNC:13176	ENSG00000185811	603023	7p12.2	IKAROS family zinc finger 1	19129520[PMID]_23751147[PMID]_19770381[PMID]_18408710[PMID]
TP53	Biomarker tested in	Assessed	HGNC:11998	ENSG00000141510	191170	17p13.1	tumor protein p53	34218582[PMID]
FLT3	Disease-causing somatic mutation(s) in	Assessed	HGNC:3765	ENSG00000122025	136351	13q12.2	fms related receptor tyrosine kinase 3	16234090[PMID]
HLA-C	Major susceptibility factor in	Assessed	HGNC:4933	ENSG00000204525	142840	6p21.33	major histocompatibility complex, class I, C	25163702[PMID]
ABL1	Part of a fusion gene in	Assessed	HGNC:76	ENSG00000097007	189980	9q34.12	ABL proto-oncogene 1, non-receptor tyrosine kinase	30561755[PMID]
BCR	Part of a fusion gene in	Assessed	HGNC:1014	ENSG00000186716	151410	22q11.23	BCR activator of RhoGEF and GTPase	23491079[PMID]

2 records

Type	Class	Value	Area	Qualification	Validation	Source
Annual incidence	Unknown	—	Worldwide	Class only	Validated	ORPHANET_WHO Classification of Tumours[OTHER]
Point prevalence	Unknown	—	Worldwide	Class only	Validated	ORPHANET_WHO Classification of Tumours[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

Orphanet has no HPO annotation for this code in this release.