Chondrosarcoma
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable, Unknown
- Age of onset
- Adult
- Status
- active
Chondrosarcoma is a malignant bone tumor arising from cartilaginous tissue, most frequently occuring at the ends of the femur and tibia, the proximal end of the humerus and the pelvis; and presenting with a palpable mass and progressive pain. Chondrosarcoma is usually slow growing at low histological grades and can be well managed by intralesional curettage or en-block wide resection.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Chondrosarcoma | |
| fr | Chondrosarcome | |
| de | Chondrosarkom | |
| es | Condrosarcoma | |
| it | Condrosarcoma | |
| nl | Chondrosarcoom | |
| pt | Condrosarcoma | |
| pl | Chrzęstniakomięsak | |
| cs | Chondrosarkom | |
| uk | Хондросаркома | |
| zh | 软骨肉瘤 | |
| tr | Kondrosarkom |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 215300 | E | validated | |
| ICD-10 | C49.9 | NTBT | attributed | validated |
| ICD-11 | 2B50 | E | specific | validated |
| MONDO | 0008977 | E | validated | |
| MeSH | D002813 | E | validated | |
| UMLS | C0008479 | E | validated | |
| GARD | 6055 | E | validated | |
| MedDRA | 10008734 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:223727Bone sarcoma
rare bone diseases; rare neoplastic diseases
No children.
Genes
1 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| EXT1 | Candidate gene tested in | Not yet assessed | HGNC:3512 | ENSG00000182197 | 608177 | 8q24.11 | exostosin glycosyltransferase 1 |
Prevalence and incidence
3 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.24 / 100 000 | Europe | Value and class | Validated | RARECARE surveillance of rare cancers in Europe[OTHER] |
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only | Validated | 22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER] |
| Lifetime Prevalence | 1-9 / 100 000 | 3.55 / 100 000 | Europe | Value and class | Validated | 22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/55880
- This record as JSON: /data/d/55880.json