Paracetamol poisoning
Synonyms: Acetaminophen poisoning
- Type
- Particular clinical situation in a disease or syndrome
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare intoxication due to a medical product occurring as a result of accidental or intentional overdosing of paracetamol (acetaminophen). Patients may develop gastroenteritis within hours and hepatotoxicity within 24 to 72 hours after ingestion, potentially leading to acute liver injury and liver failure. Possible non-hepatic sequelae include renal failure, thrombocytopenia, pancreatitis, and subendocardial myocyte necrosis. Chronic paracetamol poisoning may be asymptomatic or include all signs and symptoms potentially occurring in acute poisoning.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Paracetamol poisoning | Acetaminophen poisoning |
| fr | Intoxication au paracétamol | Intoxication au acetaminophen |
| de | Paracetamol-Vergiftung | |
| es | Intoxicación por paracetamol | |
| it | Intossicazione da paracetamolo | |
| nl | Intoxicatie door paracetamol | Intoxicatie door acetaminofen · Vergiftiging door paracetamol |
| pt | Intoxicação por paracetamol | |
| pl | Zatrucie paracetamolem | = en |
| cs | Otrava paracetamolem | Acetaminophen poisoning · Otrava acetaminofenem |
| uk | Отруєння парацетамолом | Отруєння ацетамінофеном |
| zh | 扑热息痛中毒 | 醋氨酚中毒 |
| tr | Parasetamol zehirlenmesi | Asetaminofen zehirlenmesi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | T39.1 | NTBT | attributed | validated |
| ICD-11 | NE60 | NTBT | index | validated |
| MONDO | 0018741 | E | validated | |
| UMLS | C0237963 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:306640Rare intoxication due to medical products
rare disorders due to toxic effects
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | 1-5 / 10 000 | 16 / 100 000 | Iceland | Value and class | Validated | 22827594[PMID]_15543083[PMID] |
| Point prevalence | Unknown | — | Europe | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/464458
- This record as JSON: /data/d/464458.json