Verrucous venous malformation
Synonyms: Verrucous haemangioma · Verrucous hemangioma
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Infancy, Neonatal
- Status
- active
A rare vascular anomaly characterized by congenital, solitary or grouped, red-to-purple plaques which may bleed and enlarge over time. The lesions show a predilection for the lower extremities. Histological examination reveals numerous dilated, congested capillaries and venules in the papillary dermis, often with a deep dermal component, and with increased density of variably congested capillaries and venules also in the subcutaneous tissue. The overlying epidermis displays prominent acanthosis, papillomatosis, hyperkeratosis, parakeratosis, and crusting.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Verrucous venous malformation | Verrucous haemangioma · Verrucous hemangioma |
| fr | Malformation veineuse verruqueuse | Hémangiome verruqueux |
| de | Verruköse venöse Fehlbildung | Venöse Malformation, verruköse |
| es | Malformación venosa verrugosa | Hemangioma verrrugoso |
| it | Malformazione verrucosa venosa | Emangioma verrucoso |
| nl | Verruceuze veneuze malformatie | Verruceus hemangioom |
| pt | Hemangioma verrugoso | |
| pl | Naczyniak brodawkowaty | = en |
| cs | Verukózní hemangiom | = en |
| uk | Веррукозна гемангіома | |
| zh | 疣状血管瘤 | |
| tr | Verrüköz hemanjiyom |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D18.0 | NTBT | attributed | validated |
| ICD-11 | LC52 | NTBT | index | validated |
| MONDO | 0018734 | E | validated | |
| UMLS | C0334540 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:723518Isolated combined vascular malformation
rare developmental anomalies during embryogenesis; rare circulatory system diseases - ORPHA:715334Unifocal peripheral venous malformation
rare developmental anomalies during embryogenesis; rare circulatory system diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET_25263605[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
7 annotations · validated 2019-04-29| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Obligate (100%) | ||
| HP:0001028 | Hemangioma | Diagnostic criterion |
| Frequent (79-30%) | ||
| HP:0025092 | Epidermal acanthosis | |
| HP:0045059 | Hyperkeratotic papule | |
| HP:0011123 | Inflammatory abnormality of the skin | |
| HP:0012740 | Papilloma | |
| HP:0011356 | Regional abnormality of skin | |
| HP:0200035 | Skin plaque | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 23578182[PMID]_21649690[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/464318
- This record as JSON: /data/d/464318.json