Hepatitis delta
Synonyms: HDV · Hepatitis D virus
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Hepatitis delta is a rare hepatic disease characterized by variable degrees of acute hepatitis resulting from infection with the hepatitis delta virus. Occasionally it may present a benign course, but most frequently it manifests with severe liver disease that may include fulminant liver failure, hepatic decompensation and rapid progression to cirrhosis. All patients present concomitant hepatitis B virus infection and an increased risk of developing hepatocellular carcinoma has been reported.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Hepatitis delta | HDV · Hepatitis D virus |
| fr | Hépatite delta | VHD · Virus de l'hépatite D |
| de | Hepatitis delta | HDV · Hepatitis D-Virus |
| es | Hepatitis delta | VHD · Virus de la hepatitis D |
| it | Epatite Delta | |
| nl | Hepatitis delta | Hepatitis D-virus · HDV |
| pt | Hepatite Delta | |
| pl | Zapalenie wątroby typu delta | HDV · Wirusowe zapalenie wątroby D |
| cs | Hepatitida delta | HDV · Hepatitida D |
| uk | Гепатит дельта | HDV · Вірус гепатиту D |
| zh | 丁型肝炎 | 丁型病毒肝炎 |
| tr | Hepatit delta | HDV · Hepatit D virüsü |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B17.0 | E | specific | validated |
| ICD-11 | 1E51.2 | E | specific | validated |
| MONDO | 0005789 | E | validated | |
| MeSH | D003699 | E | validated | |
| UMLS | C0011226 | E | validated | |
| MedDRA | 10019762 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:57146Rare hepatic disease
rare hepatic diseases - ORPHA:163585Rare viral disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 40 / 100 000 | Europe | Value and class | Validated | European Medicines Agency 2014[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
18 annotations · validated 2023-08-31| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0001394 | Cirrhosis | |
| HP:0031964 | Elevated circulating alanine aminotransferase concentration | |
| HP:0012115 | Hepatitis | |
| Occasional (29-5%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0001892 | Abnormal bleeding | |
| HP:0002039 | Anorexia | |
| HP:0000978 | Bruising susceptibility | |
| HP:0001289 | Confusion | |
| HP:0031956 | Elevated circulating aspartate aminotransferase concentration | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0004787 | Fulminant hepatitis | |
| HP:0001399 | Hepatic failure | |
| HP:0000952 | Jaundice | |
| HP:0033834 | Malaise | |
| HP:0002017 | Nausea and vomiting | |
| HP:0004396 | Poor appetite | |
| Very rare (<4-1%) | ||
| HP:0001402 | Hepatocellular carcinoma | |
Annotation source: 29261923[PMID]_37338616[PMID]_34239267[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/402823
- This record as JSON: /data/d/402823.json