Idiopathic avascular necrosis
Synonyms: Idiopathic AVN
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Status
- active
A rare osteonecrosis characterized by bone necrosis due to disrupted blood supply in the absence of a known cause. Affected bones include the femoral head, talus, vertebral body, humerus, and scaphoid, among others. Patients may initially be asymptomatic but subsequently present with gradually developing refractory pain, swelling, and reduced range of motion. If left untreated, the condition may progress to bone collapse with secondary degeneration, fragmentation, and pathological fracture, as well as osteoarthritis.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Idiopathic avascular necrosis | Idiopathic AVN |
| fr | Nécrose avasculaire idiopathique | AVN idiopathique |
| de | Avaskuläre Nekrose, idiopathische | Idiopathische AVN |
| es | Necrosis avascular idiopática | AVN idiopática |
| it | Necrosi avascolare idiopatica | AVN idiopatica |
| nl | Idiopathische avasculaire necrose | Idiopathische AVN |
| pt | Necrose avascular idiopática | |
| pl | Idiopatyczna martwica awaskularna | Idiopatyczna AVN |
| cs | Idiopatická avaskulární nekróza | Idiopatická AVN |
| uk | Ідіопатичний аваскулярний некроз | Ідіопатичний АВН |
| zh | 特发性缺血性坏死 | 特发性AVN |
| tr | İdiyopatik avasküler nekroz | İdyopatik AVN |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | M87.0 | E | specific | validated |
| ICD-11 | FB82.1 | NTBT | index | validated |
| MONDO | 0018380 | E | validated | |
| UMLS | C1404767 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:399302Primary avascular necrosis
rare systemic and rheumatological diseases; rare bone diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/399307
- This record as JSON: /data/d/399307.json