Neonatal antiphospholipid syndrome
Synonyms: Neonatal Hughes syndrome · Neonatal antiphospholipid antibody syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Neonatal
- Status
- active
Neonatal antiphospholipid syndrome is a rare, secondary, neonatal autoimmune disease characterized by single or recurrent episodes of venous, arterial or mixed thrombosis in a neonate whose mother does not have antiphospholipid syndrome manifestations. Patients present positive antiphospholipid antibodies and may have additional abnormalities associated (e.g. cardiac valve disease, livedo reticularis, thrombocytopenia, nephropathy, neurological manifestations).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Neonatal antiphospholipid syndrome | Neonatal Hughes syndrome · Neonatal antiphospholipid antibody syndrome |
| fr | Syndrome des antiphospholipides néonatal | APS néonatal · Neonatal APS · SAPL néonatal · Syndrome de Hughes néonatal · Syndrome des anticorps antiphospholipides néonatal |
| de | Anti-Phospholipid-Syndrom, neonatales | Anti-Phospholipid-Antikörper-Syndrom, neonatales · Hughes-Syndrom, neonatales · Neonatales APS |
| es | Síndrome antifosfolipídico neonatal | APS neonatal · SAF neonatal · Síndrome de Hughes neonatal · Síndrome neonatal por anticuerpos antifosfolípido |
| it | Sindrome neonatale da antifosfolipidi | APS neonatale · Sindrome di Hughes neonatale · Sindrome neonatale da anticorpi antifosfolipidi |
| nl | Neonataal antifosfolipidensyndroom | Neonataal APS · Neonataal antifosfolipide-antilichaamsyndroom · Neonataal syndroom van Hughes |
| pt | Síndrome antifosfolipídico neonatal | |
| pl | Zespół antyfosfolipidowy noworodków | APS noworodkowa · Zespół Hughesa noworodków · Zespół przeciwciał antyfosfolipidowych noworodków |
| cs | Neonatální antifosfolipidový syndrom | Neonatální antifosfolipidový protilátkový syndrom · Neonatální Hughesův syndrom |
| uk | Неонатальний антифосфоліпідний синдром | Синдром неонатальних антифосфоліпідних антитіл · Неонатальний синдром Хьюза |
| zh | 新生儿抗磷脂综合征 | 新生儿抗磷脂抗体综合征 |
| tr | Yenidoğan antifosfolipid sendromu | Yenidoğan Hughes sendromu · Yenidoğan antifosfolipid antikor sendromu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D68.6 | NTBT | attributed | validated |
| ICD-11 | 4A45.1 | NTBT | attributed | validated |
| MONDO | 0018357 | E | validated | |
| UMLS | C4751518 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:398091Secondary neonatal autoimmune disease
rare systemic and rheumatological diseases; rare systemic or rheumatologic diseases of childhood
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 34 cases | Worldwide | Case(s) | Validated | 24830792[PMID] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | ORPHANET_24830792[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/398097
- This record as JSON: /data/d/398097.json