Staphylococcal scalded skin syndrome
Synonyms: Generalized exfoliative disease · SSSS
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
A rare staphylococcal toxemia caused by epidermolytic toxins of <i>Staphylococcus aureus</i> and characterized by the appearance of widespread erythematous patches, on which large blisters develop. Upon rupture of these blisters, the skin appears reddish and scalded. The lesions typically begin in the face and rapidly expand to other parts of the body. The disease may be complicated by pneumonia and sepsis. It most commonly affects newborns and infants.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Staphylococcal scalded skin syndrome | Generalized exfoliative disease · SSSS |
| fr | Syndrome d'épidermolyse staphylococcique | Syndrome de la peau ébouillantée · Maladie exfoliante généralisée |
| de | Staphylococcal-Scalded-Skin-Syndrom | Dermatitis exfoliativa neonatorum Ritter von Rittershain · SSS-Syndrom · SSSS · Staphylogene toxische epidermale Nekrolyse · Staphylogenes Lyell-Syndrom · Syndrom der verbrühten Haut |
| es | Síndrome de la piel escaldada por estafilococos | Enfermedad exfoliativa generalizada · SSSS |
| it | Sindrome cutanea combustiforme da stafilococco | Malattia esfoliativa generalizzata · SSSS |
| nl | Staphylococcal scalded skin-syndroom | Gegeneraliseerde exfoliatieve ziekte · SSSS |
| pt | Doença exfoliativa generalizada | |
| pl | Gronkowcowy zespół oparzeniowy skóry | SSSS · Uogólniona choroba złuszczająca |
| cs | Stafylokokový syndrom opařené kůže | Generalizovaná exfoliativní dermatitida · SSSS |
| uk | Стафілококовий синдром обпеченої шкіри | Генералізована ексфоліативна хвороба · SSSS |
| zh | 葡萄球菌性烫伤样皮肤综合征 | 全身性剥脱性疾病 |
| tr | Stafilokokal haşlanmış deri sendromu | SSSS · Jeneralize eksfolyatif hastalık |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | L00 | E | specific | validated |
| ICD-11 | EA50.2 | E | specific | validated |
| MONDO | 0018181 | E | validated | |
| MeSH | D013206 | E | validated | |
| UMLS | C0038165 | E | validated | |
| MedDRA | 10041929 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:300579Staphylococcal toxemia
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.01 / 100 000 | Germany | Value and class | Not yet validated | 15816826[PMID] |
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/36236
- This record as JSON: /data/d/36236.json