Idiopathic hypersomnia
Synonyms: Idiopathic excessive sleepiness
- Type
- Disease
- Group
- Disorder
- Inheritance
- Unknown
- Age of onset
- All ages
- Status
- active
A rare neurologic disease characterized by an excessive daytime sleepiness with long and unrefreshing naps, and/or prolonged and undisturbed nocturnal sleep, impaired daytime alertness, and/or sleep inertia (ie, great difficulty in waking up after sleep) and where other causes have been excluded.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Idiopathic hypersomnia | Idiopathic excessive sleepiness |
| fr | Hypersomnie idiopathique | Somnolence excessive idiopathique |
| de | Hypersomnie, idiopathische | Idiopathische übermäßige Schläfrigkeit |
| es | Hipersomnia idiopática | Somnolencia excesiva idiopática |
| it | Ipersonnia idiopatica | |
| nl | Idiopathische hypersomnie | Idiopathische excessieve slaperigheid |
| pt | Hipersónia idiopática | |
| pl | Idiopatyczna hipersomnia | Hipersomnia pierwotna |
| cs | Idiopatická hypersomnie | Primární hypersomnie |
| uk | Ідіопатична гіперсомнія | Ідіопатична надмірна сонливість |
| zh | 特发性过度睡眠 | 原发性过度睡眠 |
| tr | İdiyopatik hipersomni | Primer hipersomnia |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G47.1 | E | specific | validated |
| ICD-11 | 7A21 | E | specific | validated |
| MONDO | 0018044 | E | validated | |
| MeSH | D020177 | E | validated | |
| UMLS | C0751757 | E | validated | |
| GARD | 8737 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:68354Rare sleep disorder
rare neurological diseases
No children.
Codes that Orphanet moved or referred to this one:
- ORPHA:228315OBSOLETE: Idiopathic hypersomnia with long sleep time referred to · inactive
- ORPHA:228318OBSOLETE: Idiopathic hypersomnia without long sleep time referred to · inactive
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
| Point prevalence | 1-5 / 10 000 | 30 / 100 000 | Europe | Value and class | Validated | European Medicines Agency 2015[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
12 annotations · validated 2023-09-07| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001262 | Excessive daytime somnolence | |
| HP:0100786 | Hypersomnia | |
| HP:0002360 | Sleep abnormality | |
| Frequent (79-30%) | ||
| HP:0033630 | Brain fog | |
| HP:0002354 | Memory impairment | |
| HP:0000736 | Short attention span | |
| HP:6000456 | Sleep drunkeness | |
| Occasional (29-5%) | ||
| HP:0000716 | Depression | |
| HP:0002519 | Hypnagogic hallucinations | |
| HP:0006896 | Hypnopompic hallucinations | |
| HP:0025233 | Sleep paralysis | |
| Very rare (<4-1%) | ||
| HP:0025267 | Snoring | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 36401976[PMID]_28778232[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/33208
- This record as JSON: /data/d/33208.json