Chronic actinic dermatitis
Synonyms: Actinic reticuloid · Chronic photosensitivity dermatitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
Chronic actinic dermatitis (CAD) is an immunologically mediated photodermatosis usually observed in temperate climates and that typically develops in middle-aged to elderly males. CAD is characterized by eczematous and often lichenified pruritic patches and confluent plaques located predominantly on sun-exposed areas with notable sparing of eyelids, skin folds, and postauricular skin. It is often accompanied by multiple contact allergies and usually occurs in a background of either atopic, contact allergic, or seborrheic dermatitis, although it can occur <i>de novo</i>. Resolution of photosensitivity is reported in up to 50% of individuals after 15 years or more, with contact allergies persisting.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Chronic actinic dermatitis | Actinic reticuloid · Chronic photosensitivity dermatitis |
| fr | Dermatite actinique chronique | Actinoréticulose |
| de | Dermatitis, aktinische chronische | Chronische photosensitive Dermatitis · Retikuloid, aktinisches |
| es | Dermatitis actínica crónica | Dermatitis fotosensible crónica · Reticuloide actínico |
| it | Dermatite actinica cronica | Dermatite cronica da fotosensibilità · Reticuloide attinico |
| nl | Chronische actinische dermatitis | Actinisch reticuloïd · Chonische lichtgevoeligheid-dermatitis |
| pt | Dermatite actínica crónica | Dermatite fotossensitiva crónica · Reticuloide actínico |
| pl | Przewlekłe posłoneczne zapalenie skóry | Actinic reticuloid · Przewlekłe zapalenie skóry z fotonadwrażliwości |
| cs | Chronická aktinická dermatitida | Aktinický retikuloid · Fotosenzitivní dermatitida |
| uk | Хронічний актинічний дерматит | Актинічний ретикулоїд · Хронічний фоточутливий дерматит |
| zh | 慢性光化性皮炎 | 慢性光敏性皮炎 |
| tr | Kronik aktinik dermatit | Aktinik retiküloit · Kronik fotosensitivite dermatiti |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | L57.1 | E | specific | validated |
| ICD-11 | EJ30.1 | E | specific | validated |
| MONDO | 0018025 | E | validated | |
| UMLS | C0282309 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:79390Rare photodermatosis
rare skin diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 16.7 / 100 000 | United Kingdom | Value and class | Validated | 15813653[PMID] |
| Point prevalence | 1-5 / 10 000 | — | Europe | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
12 annotations · validated 2019-10-22| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0000992 | Cutaneous photosensitivity | |
| HP:0000964 | Eczematoid dermatitis | |
| HP:0000989 | Pruritus | |
| Frequent (79-30%) | ||
| HP:0025092 | Epidermal acanthosis | |
| HP:0030350 | Erythematous papule | |
| Occasional (29-5%) | ||
| HP:0025127 | Actinic keratosis | |
| HP:0001053 | Hypopigmented skin patches | |
| HP:0007573 | Late onset atopic dermatitis | |
| HP:0100725 | Lichenification | |
| HP:0007505 | Progressive hyperpigmentation | |
| Very rare (<4-1%) | ||
| HP:0003193 | Allergic rhinitis | |
| HP:0001019 | Erythroderma | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 11843205[PMID]_24891057[PMID]_29530872[PMID]_7944510[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/330064
- This record as JSON: /data/d/330064.json