Renal medullary carcinoma
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adult
- Status
- active
Renal medullary carcinoma is a rare, aggressive subtype of renal cell carcinoma characterized by a large, white or tan, firm, infiltrative tumor with microabscess-like foci centered in the renal medulla, typically presenting with hematuria, abdominal/flank pain, weight loss and fever. It is associated with sickle cell trait and disease and metastasis to the bones and lungs is common at time of diagnosis.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Renal medullary carcinoma | |
| fr | Carcinome rénal médullaire | |
| de | Nierenkarzinom, medulläres | |
| es | Carcinoma medular renal | |
| it | Carcinoma della midollare renale | |
| nl | Renaal medullair carcinoom | |
| pt | Carcinoma medular renal | |
| pl | Rak rdzeniasty nerki | |
| cs | Medulární karcinom ledviny | |
| uk | Медулярна карцинома нирки | |
| zh | 肾髓样癌 | |
| tr | Renal medüller karsinom |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C64 | NTBT | attributed | validated |
| ICD-11 | 2C90.0 | NTBT | attributed | validated |
| MONDO | 0006260 | E | validated | |
| UMLS | C4049328 | E | validated | |
| GARD | 13175 | E | validated | |
| MedDRA | 10064886 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:217071Renal cell carcinoma
rare renal diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only | Validated | RARECARE surveillance of rare cancers in Europe[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/319319
- This record as JSON: /data/d/319319.json