Chronic intestinal failure
Synonyms: CIF
- Type
- Clinical syndrome
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Chronic intestinal failure (CIF) is a chronic type of intestinal failure characterized by a nonfunctioning small bowel (that may be reversible or irreversible) where the body is unable to maintain energy and nutritional needs through absorption of food or nutrients via the intestinal tract (despite being metabolically stable) and which therefore necessitates long-term parenteral feeding. CIF may be the result of congenital digestive diseases (such as gastroschisis, atresia of small intestine), short bowel syndrome, intra-abdominal or pelvic cancer, or progressive and devastating gastrointestinal or systemic benign diseases (such as Crohn disease).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Chronic intestinal failure | CIF |
| fr | Insuffisance intestinale chronique | CIF · IHC |
| de | Darmversagen, chronisches | CIF · Chronische intestinale Insuffizienz |
| es | Insuficiencia intestinal crónica | = en |
| it | Insufficienza intestinale cronica | = en |
| nl | Chronisch darmfalen | = en |
| pt | Insuficiência intestinal crónica | = en |
| pl | Przewlekła niewydolność jelit | = en |
| cs | Chronické selhání střev | = en |
| uk | Хронічна кишкова недостатність | = en |
| zh | 慢性肠衰竭 | 慢性肠衰竭 |
| tr | Kronik bağırsak yetmezliği | = en |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | K63.8 | NTBT | attributed | validated |
| ICD-11 | DA96.05 | NTBT | attributed | validated |
| MONDO | 0017418 | E | validated | |
| UMLS | C4274352 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:506216Rare disorder potentially indicated for bowel transplant
rare transplant-related disorders - ORPHA:117569Rare intestinal disease
rare gastroenterological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Prevalence at birth | 6-9 / 10 000 | 86 / 100 000 | Italy | Value and class | Validated | 18589446[PMID] |
| Point prevalence | 1-5 / 10 000 | 42.4691 / 100 000 | Italy | Value and class | Validated | 36215864[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/294422
- This record as JSON: /data/d/294422.json