ORPHA:293375
Grayson-Wilbrandt corneal dystrophy
Synonyms: GWCD
- Type
- Disease
- Group
- Disorder
- Inheritance
- Autosomal dominant
- Age of onset
- Adolescent, Adult, Childhood
- Status
- active
Grayson-Wilbrandt corneal dystrophy (GWCD) is an extremely rare form of corneal dystrophy characterized by variable patterns of opacification in the Bowman layer of the cornea which extend anteriorly into the epithelium with decreased to normal visual acuity.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Grayson-Wilbrandt corneal dystrophy | GWCD |
| fr | Dystrophie cornéenne de Grayson-Wilbrandt | = en |
| de | Grayson-Wilbrandt-Hornhautdystrophie | = en |
| es | Distrofia corneal de Grayson-Wilbrandt | = en |
| it | Distrofia corneale di Grayson-Wilbrandt | = en |
| nl | Grayson-Wilbrandt-corneadystrofie | = en |
| pt | Distrofia corneana de Grayson-Wilbrandt | = en |
| pl | Dystrofia rogówki Graysona i Wilbrandta | = en |
| cs | Graysonova-Wilbrandtova dystrofie rohovky | GWCD · Grayson-Wilbrandtova dystrofie rohovky |
| uk | Дистрофія рогівки Грейсона-Вільбрандта | = en |
| zh | Grayson-Wilbrandt角膜营养不良 | Grayson-Wilbrandt角膜营养不良 |
| tr | Grayson-Wilbrandt kornea distrofisi | = en |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | H18.5 | NTBT | attributed | validated |
| ICD-11 | 9A70.Y | NTBT | index | validated |
| MONDO | 0017391 | E | validated | |
| UMLS | C4305579 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:522562Genetic superficial corneal dystrophy
rare genetic diseases - ORPHA:98625Superficial corneal dystrophy
rare ophthalmic disorders
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 1 families | Worldwide | Family(ies) | Validated | 8230838[PMID]_[EXPERT] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | ORPHANET_8230838[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/293375
- This record as JSON: /data/d/293375.json