ORPHA:291
Congenital varicella syndrome
Synonyms: Antenatal varicella virus infection · Mother-to-child transmission of varicella syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Antenatal, Neonatal
- Status
- active
A rare acquired developmental anomaly syndrome characterized by skin, neurological, ocular, limbs and growth defects secondary to maternal Varicella-Zoster Virus (VZV) infection.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Congenital varicella syndrome | Antenatal varicella virus infection · Mother-to-child transmission of varicella syndrome |
| fr | Syndrome de varicelle congénitale | Embryopathie au virus de la varicelle |
| de | Varizellen-Syndrom, kongenitales | Varicella-Virus-Infektion, pränatale · Varizellen-Embryo-Fetopathie · Varizellen-Syndrom durch Mutter-Kind-Übertragung · Varizellen-Syndrom, fetales |
| es | Síndrome de varicela congénita | Infección prenatal por el virus de la varicela · Transmisión materna del síndrome de varicela · Transmisión materna del síndrome de varicela congénita |
| it | Sindrome da varicella fetale | Infezione prenatale da virus della varicella |
| nl | Congenitaal varicellasyndroom | Prenatale infectie door varicellavirus · Transmissie van moeder op kind van varicellasyndroom |
| pt | Síndrome varicela congénita | Infeção pré-natal pelo vírus da varicela · Síndrome varicela fetal |
| pl | Zespół wrodzonej ospy wietrznej | Prenatalne zakażenie wirusem ospy wietrznej · Prenatalne zakażenie wirusem ospy wietrznej |
| cs | Vrozený varicellový syndrom | Prenatální nákaza virem vericelly |
| uk | Вроджений синдром вітряної віспи | Антенатальна інфекція вірусу вітряної віспи · Передача вітряної віспи від матері до дитини |
| zh | 先天性水痘综合征 | 母婴传播型水痘综合征 |
| tr | Doğumsal suçiçeği sendromu | Antenatal suçiçeği virüsü enfeksiyonu · Su çiçeği sendromunun anneden çocuğa bulaşması |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | P35.8 | NTBT | inclusion | validated |
| ICD-11 | KA62.2 | NTBT | index | validated |
| MONDO | 0017372 | E | validated | |
| UMLS | C4275251 | E | validated | |
| GARD | 45 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:232035Infectious embryofetopathy
rare developmental anomalies during embryogenesis; rare infectious diseases; rare teratologic disorders - ORPHA:98641Syndromic cataract
rare ophthalmic disorders
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 130 cases | Worldwide | Case(s) | Validated | 26965725[PMID] | |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET_26965725[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
9 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0000987 | Atypical scarring of skin | |
| HP:0001511 | Intrauterine growth retardation | |
| Frequent (79-30%) | ||
| HP:0000518 | Cataract | |
| HP:0002120 | Cerebral cortical atrophy | |
| HP:0001263 | Global developmental delay | |
| HP:0001249 | Intellectual disability | |
| HP:0000252 | Microcephaly | |
| HP:0002983 | Micromelia | |
| HP:0000568 | Microphthalmia | |
Run the differential on the 2 obligate / very frequent terms
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/291
- This record as JSON: /data/d/291.json