raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:276429

Hypnic headache

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
Adult, Childhood, Elderly
Status
active

A rare headache characterized by recurrent brief, intense headache attacks occurring exclusively during sleep, typically at the same time of the night, causing the patient to wake up. The pain usually lasts more than 15 minutes after waking. It is mostly bilateral and may be associated with nausea, photophobia, or phonophobia, while characteristically no autonomic symptoms are present.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enHypnic headache
frCéphalée hypnique
deKopfschmerz, schlafgebundener
esCefalea hípnica
itCefalea ipnica
nlHypnische hoofdpijn
ptCefaleia hipnica
plŚródsenny ból głowy
csHypnická bolest hlavy
ukГіпнічний головний біль
zh睡眠性头痛
trHipnik baş ağrısı

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10G44.8NTBTattributedvalidated
ICD-118A83NTBTindexvalidated
MONDO0017181Evalidated
UMLSC0752150Evalidated
GARD10796Evalidated
MedDRA10088606Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card