Nevus of Ito
Synonyms: Nevus fuscocaeruleus acromiodeltoideus
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Nevus of Ito is a benign dermal melanocytosis occurring most frequently in the Asian populations and characterized by unilateral, asymptomatic, blue, gray or brown skin pigmentation within the acromioclavicular and upper chest area (involving the side of the neck, the supraclavicular and scapular areas, and the shoulder region). It is usually diagnosed in early infancy and in early adolescence. Nevus of Ito may progressively enlarge and darken in color (particularly with puberty) and its appearance usually remains stable once adulthood is reached. Spontaneous regression does not occur. Malignant melanoma has rarely been reported within a nevus of Ito. It shares the clinical features of nevus of Ota, except its anatomic location and in rare occasions, may occur together with the latter.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Nevus of Ito | Nevus fuscocaeruleus acromiodeltoideus |
| fr | Naevus d'Ito | Naevus fuscocaeruleus acromiodeltoideus |
| de | Naevus Ito | Naevus fuscocaeruleus acromiodeltoides |
| es | Nevo de Ito | Nevo de Ota acromiodeltoide |
| it | Nevo di Ito | Nevo fuscoceruleo acromiodeltoideo |
| nl | Naevus van Ito | Naevus fuscocaeruleus acromiodeltoideus |
| pt | Nevus de Ito | |
| pl | Znamię Ito | = en |
| cs | Itův névus | = en |
| uk | Невус Іто | Невус фускокаерулеус акроміодельтоідеус (Nevus fuscocaeruleus acromiodeltoideus) |
| zh | 伊藤痣 | 肩峰三角肌蓝褐痣 |
| tr | Ito nevüsü | Nevüs fussuloserulös akromiodeltoides |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D22.6 | NTBT | attributed | validated |
| ICD-11 | LC10 | NTBT | index | validated |
| MONDO | 0016985 | E | validated | |
| UMLS | C0022283 | E | validated | |
| GARD | 10830 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:294057Rare nevus
rare skin diseases; rare neoplastic diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 1.17 / 100 000 | Europe | Value and class | Not yet validated | ORPHANET |
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
3 annotations · validated 2024-09-30| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0003764 | Nevus | |
| Very rare (<4-1%) | ||
| HP:0012056 | Cutaneous melanoma | |
| Excluded (0%) | ||
| HP:0025534 | Ocular melanocytosis | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 32809409[PMID]_26260725[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/263432
- This record as JSON: /data/d/263432.json