Familial supernumerary nipples
Synonyms: Isolated polythelia
- Type
- Morphological anomaly
- Group
- Disorder
- Age of onset
- Infancy, Neonatal
- Status
- active
Familial supernumerary nipples is a rare breast malformation characterized by the presence, in various members of a single family, of one or more nipple(s) and/or their related tissue, in addition to the normal bilateral chest nipples. The anomaly is usually situated along the embryonic milk line, from axillae to inguinal regions, but other locations are also possible. Association with dental abnormalities, Becker nevus, renal or underlying breast tissue malignancy and genitourinary malformations has been reported.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Familial supernumerary nipples | Isolated polythelia |
| fr | Mamelon surnuméraire héréditaire | Polythélie isolée |
| de | Mamillen, überzählige, familiäre Form | Polythelie, isolierte |
| es | Pezones supernumerarios familiares | Politelia aislada |
| it | Capezzoli soprannumerari familiari | |
| nl | Familiale surnumeraire tepels | Geïsoleerde polythelie |
| pt | Mamilos supranumerários familiar | Politelia familiar |
| pl | Rodzinne dodatkowe gruczoły sutkowe | Politelia izolowana |
| cs | Nadpočetná bradavka | Izolovaná polytelie |
| uk | Сімейні надлишкові соски | Ізольована політелія |
| zh | 家族遗传性多乳头 | 孤立型多乳头畸形 |
| tr | Ailesel süpernümerik meme uçları | İzole politeli |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 163700 | E | validated | |
| ICD-10 | Q83.3 | NTBT | attributed | validated |
| ICD-11 | LB63 | NTBT | attributed | validated |
| MONDO | 0008101 | E | validated | |
| UMLS | C4707878 | E | validated | |
| GARD | 2259 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:180170Excess breast volume or number
rare gynecological and obstetric diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 46 cases | Worldwide | Case(s) | Validated | 9809822[PMID]_1638072[PMID]_28361071[PMID]_20465693[PMID]_8603338[PMID]_11421419[PMID]_12514363[PMID] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | 9809822[PMID]_1638072[PMID]_28361071[PMID]_20465693[PMID]_8603338[PMID]_11421419[PMID]_12514363[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
2 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002558 | Supernumerary nipple | |
| Occasional (29-5%) | ||
| HP:0000119 | Abnormality of the genitourinary system | |
Run the differential on the 1 obligate / very frequent terms
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2456
- This record as JSON: /data/d/2456.json